Tags

Type your tag names separated by a space and hit enter

Intrauterine contraceptive devices in diabetic women.
Lancet 1982; 1(8271):530-5Lct

Abstract

11 of 30 (36.6%) insulin-dependent diabetic women fitted with intrauterine contraceptive devices (IUCDs) became pregnant within 1 year, whereas the pregnancy rate for non-diabetic women fitted with the same types of IUCD by the same consultant gynaecologists over a similar time period was 4 per 100 women years (4%). As soon as the high risk was recognised, devices were removed (2 from diabetic women who were pregnant and 19 from non-pregnant diabetic women), and patients were advised about other methods of contraception. The IUCDs were examined in a scanning electron microscope with X-ray microprobe analysis to measure the amount of copper eroded from the wire, the extent of the encrustation (if any) deposited on the wire, and the composition of the deposit, and the data were compared with those for 111 devices removed from non-diabetic women, 40% of the IUCDs from diabetic women had sulphur and chloride in the deposit, compared with 15.3% of IUCDs from normal women, and fewer IUCDs from diabetic women had calcareous deposits. In devices from normal women, erosion and deposition seemed to occur independently, but in IUCDs from diabetic women, there was high erosion, there were also large deposits, and where there was little deposit, the erosion was slight. 7 of 14 IUCDs taken from normal women who had become pregnant with an IUCD in situ had a high sulphur plus chloride deposit; none of these IUCDs had a predominantly calcareous deposit compared with 19.8% of the IUCDs from non-pregnant normal women. The evidence militates against the insertion of IUCDs in diabetic patients and indicated that, even in non-diabetic women, there may be small groups for whom the risk of becoming pregnant is very high.

Authors

No affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info available

Pub Type(s)

Journal Article

Language

eng

PubMed ID

6120391

Citation

Gosden, C, et al. "Intrauterine Contraceptive Devices in Diabetic Women." Lancet (London, England), vol. 1, no. 8271, 1982, pp. 530-5.
Gosden C, Steel J, Ross A, et al. Intrauterine contraceptive devices in diabetic women. Lancet. 1982;1(8271):530-5.
Gosden, C., Steel, J., Ross, A., & Springbett, A. (1982). Intrauterine contraceptive devices in diabetic women. Lancet (London, England), 1(8271), pp. 530-5.
Gosden C, et al. Intrauterine Contraceptive Devices in Diabetic Women. Lancet. 1982 Mar 6;1(8271):530-5. PubMed PMID: 6120391.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Intrauterine contraceptive devices in diabetic women. AU - Gosden,C, AU - Steel,J, AU - Ross,A, AU - Springbett,A, PY - 1982/3/6/pubmed PY - 1982/3/6/medline PY - 1982/3/6/entrez KW - Age Factors KW - Contraception KW - Contraception Continuation KW - Contraceptive Methods--changes KW - Contraceptive Methods--complications KW - Contraceptive Mode Of Action KW - Copper--analysis KW - Diabetes Mellitus KW - Diseases KW - Evaluation KW - Examinations And Diagnoses KW - Family Planning KW - Ingredients And Chemicals KW - Inorganic Chemicals KW - Iud, Copper Releasing KW - Iud, Unmedicated KW - Iud--changes KW - Iud--complications KW - Laboratory Examinations And Diagnoses KW - Laboratory Procedures KW - Metals KW - Parity KW - Polyethylene KW - Population Characteristics KW - Pregnancy, Unplanned SP - 530 EP - 5 JF - Lancet (London, England) JO - Lancet VL - 1 IS - 8271 N2 - 11 of 30 (36.6%) insulin-dependent diabetic women fitted with intrauterine contraceptive devices (IUCDs) became pregnant within 1 year, whereas the pregnancy rate for non-diabetic women fitted with the same types of IUCD by the same consultant gynaecologists over a similar time period was 4 per 100 women years (4%). As soon as the high risk was recognised, devices were removed (2 from diabetic women who were pregnant and 19 from non-pregnant diabetic women), and patients were advised about other methods of contraception. The IUCDs were examined in a scanning electron microscope with X-ray microprobe analysis to measure the amount of copper eroded from the wire, the extent of the encrustation (if any) deposited on the wire, and the composition of the deposit, and the data were compared with those for 111 devices removed from non-diabetic women, 40% of the IUCDs from diabetic women had sulphur and chloride in the deposit, compared with 15.3% of IUCDs from normal women, and fewer IUCDs from diabetic women had calcareous deposits. In devices from normal women, erosion and deposition seemed to occur independently, but in IUCDs from diabetic women, there was high erosion, there were also large deposits, and where there was little deposit, the erosion was slight. 7 of 14 IUCDs taken from normal women who had become pregnant with an IUCD in situ had a high sulphur plus chloride deposit; none of these IUCDs had a predominantly calcareous deposit compared with 19.8% of the IUCDs from non-pregnant normal women. The evidence militates against the insertion of IUCDs in diabetic patients and indicated that, even in non-diabetic women, there may be small groups for whom the risk of becoming pregnant is very high. SN - 0140-6736 UR - https://www.unboundmedicine.com/medline/citation/6120391/Intrauterine_contraceptive_devices_in_diabetic_women_ L2 - https://linkinghub.elsevier.com/retrieve/pii/S0140-6736(82)92044-X DB - PRIME DP - Unbound Medicine ER -