Breast cancer in young women and use of oral contraceptives: possible modifying effect of formulation and age at use.Lancet. 1983 Oct 22; 2(8356):926-30.Lct
Abstract
A case-control study of 314 breast cancer patients aged less than 37 at diagnosis and 314 individually matched controls was done to assess the influence of oral-contraceptive (OC) use on the risk of the disease. Long-term use before age 25 of combination-type OCs with a "high" content of the progestogen component was associated with increased risk of breast cancer: the relative risk was approximately 4 after 5 years of such use, and 9 cases and no controls had used such combination-type OCs for more than 6 years before age 25. Use of combination-type OCs with a "low" progestogen component appears to increase breast-cancer risk little or not at all.
Links
MeSH
Pub Type(s)
Comparative Study
Journal Article
Research Support, U.S. Gov't, P.H.S.
Language
eng
PubMed ID
6138501
Citation
Pike, M C., et al. "Breast Cancer in Young Women and Use of Oral Contraceptives: Possible Modifying Effect of Formulation and Age at Use." Lancet (London, England), vol. 2, no. 8356, 1983, pp. 926-30.
Pike MC, Henderson BE, Krailo MD, et al. Breast cancer in young women and use of oral contraceptives: possible modifying effect of formulation and age at use. Lancet. 1983;2(8356):926-30.
Pike, M. C., Henderson, B. E., Krailo, M. D., Duke, A., & Roy, S. (1983). Breast cancer in young women and use of oral contraceptives: possible modifying effect of formulation and age at use. Lancet (London, England), 2(8356), 926-30.
Pike MC, et al. Breast Cancer in Young Women and Use of Oral Contraceptives: Possible Modifying Effect of Formulation and Age at Use. Lancet. 1983 Oct 22;2(8356):926-30. PubMed PMID: 6138501.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR
T1 - Breast cancer in young women and use of oral contraceptives: possible modifying effect of formulation and age at use.
AU - Pike,M C,
AU - Henderson,B E,
AU - Krailo,M D,
AU - Duke,A,
AU - Roy,S,
PY - 1983/10/22/pubmed
PY - 1983/10/22/medline
PY - 1983/10/22/entrez
KW - Age Factors
KW - Biology
KW - Birth Order
KW - Breast Cancer
KW - Cancer
KW - Contraception
KW - Contraceptive Agents
KW - Contraceptive Agents, Female
KW - Contraceptive Methods--side effects
KW - Control Groups
KW - Demographic Factors
KW - Diseases
KW - Endocrine System
KW - Estrogens
KW - Family And Household
KW - Family Characteristics
KW - Family Planning
KW - Family Relationships
KW - Fertility
KW - Fertility Measurements
KW - First Birth
KW - High Risk Women
KW - Hormones
KW - Menarche
KW - Menopause
KW - Neoplasms
KW - Oral Contraceptives, Combined
KW - Oral Contraceptives--side effects
KW - Physiology
KW - Population
KW - Population Characteristics
KW - Population Dynamics
KW - Pregnancy History
KW - Progestational Hormones
KW - Progesterone
KW - Reproduction
KW - Reproductive Control Agents
KW - Research Methodology
KW - Time Factors
SP - 926
EP - 30
JF - Lancet (London, England)
JO - Lancet
VL - 2
IS - 8356
N2 - A case-control study of 314 breast cancer patients aged less than 37 at diagnosis and 314 individually matched controls was done to assess the influence of oral-contraceptive (OC) use on the risk of the disease. Long-term use before age 25 of combination-type OCs with a "high" content of the progestogen component was associated with increased risk of breast cancer: the relative risk was approximately 4 after 5 years of such use, and 9 cases and no controls had used such combination-type OCs for more than 6 years before age 25. Use of combination-type OCs with a "low" progestogen component appears to increase breast-cancer risk little or not at all.
SN - 0140-6736
UR - https://www.unboundmedicine.com/medline/citation/6138501/Breast_cancer_in_young_women_and_use_of_oral_contraceptives:_possible_modifying_effect_of_formulation_and_age_at_use_
L2 - https://linkinghub.elsevier.com/retrieve/pii/S0140-6736(83)90450-6
DB - PRIME
DP - Unbound Medicine
ER -