Tags

Type your tag names separated by a space and hit enter

Effect of anti-allergic compounds on anaphylactic histamine secretion from rat peritoneal mast cells in the presence and absence of exogenous calcium.
Immunology. 1982 Jun; 46(2):361-7.I

Abstract

The anti-allergic drugs theophylline, doxantrazole, quercetin, 8-bromo cyclic AMP, and disodium cromoglycate prevented anaphylactic histamine release from rat peritoneal mast cells in both the presence and absence of extracellular calcium. The activity of the test compounds under the latter conditions cannot be simply explained in terms of their postulated ability to block movement of the cation from the external environment into the cell. Alternative modes of action are thus considered.

Links

PMC Free PDF
PMC Free Full Text

Authors

White JR
No affiliation info available
Pearce FL
No affiliation info available

MeSH

8-Bromo Cyclic Adenosine MonophosphateAnaphylaxisAnimalsAscitic FluidBronchodilator AgentsCalciumCromolyn SodiumCyclic AMPDose-Response Relationship, DrugFemaleHistamine ReleaseMaleMast CellsQuercetinRatsRats, Inbred StrainsTheophyllineThioxanthenesXanthones

Pub Type(s)

Journal Article
Research Support, Non-U.S. Gov't

Language

eng

PubMed ID

6177625

Citation

White, J R., and F L. Pearce. "Effect of Anti-allergic Compounds On Anaphylactic Histamine Secretion From Rat Peritoneal Mast Cells in the Presence and Absence of Exogenous Calcium." Immunology, vol. 46, no. 2, 1982, pp. 361-7.
White JR, Pearce FL. Effect of anti-allergic compounds on anaphylactic histamine secretion from rat peritoneal mast cells in the presence and absence of exogenous calcium. Immunology. 1982;46(2):361-7.
White, J. R., & Pearce, F. L. (1982). Effect of anti-allergic compounds on anaphylactic histamine secretion from rat peritoneal mast cells in the presence and absence of exogenous calcium. Immunology, 46(2), 361-7.
White JR, Pearce FL. Effect of Anti-allergic Compounds On Anaphylactic Histamine Secretion From Rat Peritoneal Mast Cells in the Presence and Absence of Exogenous Calcium. Immunology. 1982;46(2):361-7. PubMed PMID: 6177625.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Effect of anti-allergic compounds on anaphylactic histamine secretion from rat peritoneal mast cells in the presence and absence of exogenous calcium. AU - White,J R, AU - Pearce,F L, PY - 1982/6/1/pubmed PY - 1982/6/1/medline PY - 1982/6/1/entrez SP - 361 EP - 7 JF - Immunology JO - Immunology VL - 46 IS - 2 N2 - The anti-allergic drugs theophylline, doxantrazole, quercetin, 8-bromo cyclic AMP, and disodium cromoglycate prevented anaphylactic histamine release from rat peritoneal mast cells in both the presence and absence of extracellular calcium. The activity of the test compounds under the latter conditions cannot be simply explained in terms of their postulated ability to block movement of the cation from the external environment into the cell. Alternative modes of action are thus considered. SN - 0019-2805 UR - https://www.unboundmedicine.com/medline/citation/6177625/Effect_of_anti_allergic_compounds_on_anaphylactic_histamine_secretion_from_rat_peritoneal_mast_cells_in_the_presence_and_absence_of_exogenous_calcium_ L2 - https://www.ncbi.nlm.nih.gov/pmc/articles/pmid/6177625/ DB - PRIME DP - Unbound Medicine ER -