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Autoimmune effector cells. IV. Induction of experimental allergic encephalomyelitis in Lewis rats without adjuvant.
J Immunol. 1983 Feb; 130(2):732-4.JI

Abstract

Experimental autoimmune encephalomyelitis (EAE) was induced in Lewis rats without the aid of adjuvant. Radioresistant cells were activated from spleens of nonimmune donor rats by in vitro culture with myelin basic protein (BP). After adoptive transfer, these cells recruited EAE effector cells in normal syngeneic recipients, as demonstrated after transfer to secondary hosts. The induction of EAE without adjuvant may lead to a better understanding of the mechanisms of autoimmune disease induction.

Authors

No affiliation info availableNo affiliation info availableNo affiliation info available

Pub Type(s)

Journal Article
Research Support, Non-U.S. Gov't
Research Support, U.S. Gov't, P.H.S.

Language

eng

PubMed ID

6184402

Citation

Holda, J H., et al. "Autoimmune Effector Cells. IV. Induction of Experimental Allergic Encephalomyelitis in Lewis Rats Without Adjuvant." Journal of Immunology (Baltimore, Md. : 1950), vol. 130, no. 2, 1983, pp. 732-4.
Holda JH, Silberg D, Swanborg RH. Autoimmune effector cells. IV. Induction of experimental allergic encephalomyelitis in Lewis rats without adjuvant. J Immunol. 1983;130(2):732-4.
Holda, J. H., Silberg, D., & Swanborg, R. H. (1983). Autoimmune effector cells. IV. Induction of experimental allergic encephalomyelitis in Lewis rats without adjuvant. Journal of Immunology (Baltimore, Md. : 1950), 130(2), 732-4.
Holda JH, Silberg D, Swanborg RH. Autoimmune Effector Cells. IV. Induction of Experimental Allergic Encephalomyelitis in Lewis Rats Without Adjuvant. J Immunol. 1983;130(2):732-4. PubMed PMID: 6184402.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Autoimmune effector cells. IV. Induction of experimental allergic encephalomyelitis in Lewis rats without adjuvant. AU - Holda,J H, AU - Silberg,D, AU - Swanborg,R H, PY - 1983/2/1/pubmed PY - 1983/2/1/medline PY - 1983/2/1/entrez SP - 732 EP - 4 JF - Journal of immunology (Baltimore, Md. : 1950) JO - J Immunol VL - 130 IS - 2 N2 - Experimental autoimmune encephalomyelitis (EAE) was induced in Lewis rats without the aid of adjuvant. Radioresistant cells were activated from spleens of nonimmune donor rats by in vitro culture with myelin basic protein (BP). After adoptive transfer, these cells recruited EAE effector cells in normal syngeneic recipients, as demonstrated after transfer to secondary hosts. The induction of EAE without adjuvant may lead to a better understanding of the mechanisms of autoimmune disease induction. SN - 0022-1767 UR - https://www.unboundmedicine.com/medline/citation/6184402/Autoimmune_effector_cells__IV__Induction_of_experimental_allergic_encephalomyelitis_in_Lewis_rats_without_adjuvant_ L2 - https://www.jimmunol.org/lookup/pmidlookup?view=long&pmid=6184402 DB - PRIME DP - Unbound Medicine ER -