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Effect of some antianaphylactic drugs on histamine release from rat mast cells induced by the ionophore A 23 187.
Allergol Immunopathol (Madr). 1982 Jul-Aug; 10(4):257-62.AI

Abstract

Concerning DSCG and its action on histamine release induced by the ionophore A 23 187, the reported results are controversial; hence we have studied it further. Experiments were performed using mixed peritoneal cells of the rat. Released and residual histamine were measured fluorimetrically. Pyridoxine and disodium cromoglycate reduced histamine release from rat mast cells induced by a) dextran plus phosphatidyl serine and b) the calcium ionophore A 23 187. The relevance of these results to the mechanism of action of the drugs is discussed.

Authors

No affiliation info availableNo affiliation info available

Pub Type(s)

Journal Article

Language

eng

PubMed ID

6184977

Citation

García Mesa, M, and R González Alvarez. "Effect of some Antianaphylactic Drugs On Histamine Release From Rat Mast Cells Induced By the Ionophore a 23 187." Allergologia Et Immunopathologia, vol. 10, no. 4, 1982, pp. 257-62.
García Mesa M, González Alvarez R. Effect of some antianaphylactic drugs on histamine release from rat mast cells induced by the ionophore A 23 187. Allergol Immunopathol (Madr). 1982;10(4):257-62.
García Mesa, M., & González Alvarez, R. (1982). Effect of some antianaphylactic drugs on histamine release from rat mast cells induced by the ionophore A 23 187. Allergologia Et Immunopathologia, 10(4), 257-62.
García Mesa M, González Alvarez R. Effect of some Antianaphylactic Drugs On Histamine Release From Rat Mast Cells Induced By the Ionophore a 23 187. Allergol Immunopathol (Madr). 1982 Jul-Aug;10(4):257-62. PubMed PMID: 6184977.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Effect of some antianaphylactic drugs on histamine release from rat mast cells induced by the ionophore A 23 187. AU - García Mesa,M, AU - González Alvarez,R, PY - 1982/7/1/pubmed PY - 1982/7/1/medline PY - 1982/7/1/entrez SP - 257 EP - 62 JF - Allergologia et immunopathologia JO - Allergol Immunopathol (Madr) VL - 10 IS - 4 N2 - Concerning DSCG and its action on histamine release induced by the ionophore A 23 187, the reported results are controversial; hence we have studied it further. Experiments were performed using mixed peritoneal cells of the rat. Released and residual histamine were measured fluorimetrically. Pyridoxine and disodium cromoglycate reduced histamine release from rat mast cells induced by a) dextran plus phosphatidyl serine and b) the calcium ionophore A 23 187. The relevance of these results to the mechanism of action of the drugs is discussed. SN - 0301-0546 UR - https://www.unboundmedicine.com/medline/citation/6184977/Effect_of_some_antianaphylactic_drugs_on_histamine_release_from_rat_mast_cells_induced_by_the_ionophore_A_23_187_ L2 - https://medlineplus.gov/antibiotics.html DB - PRIME DP - Unbound Medicine ER -