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[Use of systemic retinoids in dermatology].
Wien Klin Wochenschr. 1983 Dec 09; 95(23):817-22.WK

Abstract

The naturally occurring retinoids (vitamin A alcohol = retinol and all-trans-retinoic acid) have been largely replaced by synthetic retinoids in recent years as systemic drugs for use in dermatology. At the present time, two synthetic retinoids are commercially available: etretinate (Tigason) and isotretinoin (Accutane). These compounds-which have a more favourable therapeutic index than the naturally occurring retinoids-ushered in a new era of dermatological therapy by their potent antikeratinizing, antiseborrhoeic (only isotretinoin) and antineoplastic action. The broadest indications for the use of these retinoids are psoriasis (etretinate) and cystic acne (isotretinoin), whereas the most dramatic effects are encountered in a number of severe ichthyosiform disorders. Another important, although at present not clearly defined role of the retinoids is in the prophylaxis of skin tumours.

Authors

No affiliation info available

Pub Type(s)

English Abstract
Journal Article

Language

ger

PubMed ID

6230801

Citation

Fritsch, P. "[Use of Systemic Retinoids in Dermatology]." Wiener Klinische Wochenschrift, vol. 95, no. 23, 1983, pp. 817-22.
Fritsch P. [Use of systemic retinoids in dermatology]. Wien Klin Wochenschr. 1983;95(23):817-22.
Fritsch, P. (1983). [Use of systemic retinoids in dermatology]. Wiener Klinische Wochenschrift, 95(23), 817-22.
Fritsch P. [Use of Systemic Retinoids in Dermatology]. Wien Klin Wochenschr. 1983 Dec 9;95(23):817-22. PubMed PMID: 6230801.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - [Use of systemic retinoids in dermatology]. A1 - Fritsch,P, PY - 1983/12/9/pubmed PY - 1983/12/9/medline PY - 1983/12/9/entrez SP - 817 EP - 22 JF - Wiener klinische Wochenschrift JO - Wien Klin Wochenschr VL - 95 IS - 23 N2 - The naturally occurring retinoids (vitamin A alcohol = retinol and all-trans-retinoic acid) have been largely replaced by synthetic retinoids in recent years as systemic drugs for use in dermatology. At the present time, two synthetic retinoids are commercially available: etretinate (Tigason) and isotretinoin (Accutane). These compounds-which have a more favourable therapeutic index than the naturally occurring retinoids-ushered in a new era of dermatological therapy by their potent antikeratinizing, antiseborrhoeic (only isotretinoin) and antineoplastic action. The broadest indications for the use of these retinoids are psoriasis (etretinate) and cystic acne (isotretinoin), whereas the most dramatic effects are encountered in a number of severe ichthyosiform disorders. Another important, although at present not clearly defined role of the retinoids is in the prophylaxis of skin tumours. SN - 0043-5325 UR - https://www.unboundmedicine.com/medline/citation/6230801/[Use_of_systemic_retinoids_in_dermatology]_ L2 - https://medlineplus.gov/skinconditions.html DB - PRIME DP - Unbound Medicine ER -
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