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Effect of saline loading during heat acclimatization on adrenocortical hormone levels.

Abstract

Six male subjects were acclimatized to heat; once they were given sufficient 1% saline to prevent the occurrence of a salt deficit during acclimatization, and another time they were given no saline. Plasma aldosterone (PA), plasma cortisol (PC), plasma renin activity (PRA), and plasma electrolytes were measured before, during, and after and sweat electrolytes before and after the 11-day acclimatization program. PRA and PA were significantly increased by the acute stress of heat and exercise but were unaffected by acclimatization. These increases were attenuated, but not prevented, by drinking saline, whereas sweat [Na] and PC were reduced by acclimatization but were unaffected by saline. Thus adrenocortical activity has been shown not to be increased after heat acclimatization, and mineralocorticoid activity, although potentiated by a Na deficit, appears to be determined primarily by the acute stress of heat and of exercise. Hence, the increased Na conservation with acclimatization is likely to be a normal response to heat and exercise even in the absence of a negative Na balance.

Authors

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Pub Type(s)

Journal Article

Language

eng

PubMed ID

6265414

Citation

Davies, J A., et al. "Effect of Saline Loading During Heat Acclimatization On Adrenocortical Hormone Levels." Journal of Applied Physiology: Respiratory, Environmental and Exercise Physiology, vol. 50, no. 3, 1981, pp. 605-12.
Davies JA, Harrison MH, Cochrane LA, et al. Effect of saline loading during heat acclimatization on adrenocortical hormone levels. J Appl Physiol Respir Environ Exerc Physiol. 1981;50(3):605-12.
Davies, J. A., Harrison, M. H., Cochrane, L. A., Edwards, R. J., & Gibson, T. M. (1981). Effect of saline loading during heat acclimatization on adrenocortical hormone levels. Journal of Applied Physiology: Respiratory, Environmental and Exercise Physiology, 50(3), 605-12.
Davies JA, et al. Effect of Saline Loading During Heat Acclimatization On Adrenocortical Hormone Levels. J Appl Physiol Respir Environ Exerc Physiol. 1981;50(3):605-12. PubMed PMID: 6265414.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Effect of saline loading during heat acclimatization on adrenocortical hormone levels. AU - Davies,J A, AU - Harrison,M H, AU - Cochrane,L A, AU - Edwards,R J, AU - Gibson,T M, PY - 1981/3/1/pubmed PY - 1981/3/1/medline PY - 1981/3/1/entrez SP - 605 EP - 12 JF - Journal of applied physiology: respiratory, environmental and exercise physiology JO - J Appl Physiol Respir Environ Exerc Physiol VL - 50 IS - 3 N2 - Six male subjects were acclimatized to heat; once they were given sufficient 1% saline to prevent the occurrence of a salt deficit during acclimatization, and another time they were given no saline. Plasma aldosterone (PA), plasma cortisol (PC), plasma renin activity (PRA), and plasma electrolytes were measured before, during, and after and sweat electrolytes before and after the 11-day acclimatization program. PRA and PA were significantly increased by the acute stress of heat and exercise but were unaffected by acclimatization. These increases were attenuated, but not prevented, by drinking saline, whereas sweat [Na] and PC were reduced by acclimatization but were unaffected by saline. Thus adrenocortical activity has been shown not to be increased after heat acclimatization, and mineralocorticoid activity, although potentiated by a Na deficit, appears to be determined primarily by the acute stress of heat and of exercise. Hence, the increased Na conservation with acclimatization is likely to be a normal response to heat and exercise even in the absence of a negative Na balance. SN - 0161-7567 UR - https://www.unboundmedicine.com/medline/citation/6265414/Effect_of_saline_loading_during_heat_acclimatization_on_adrenocortical_hormone_levels_ L2 - https://antibodies.cancer.gov/detail/CPTC-Calcyclin-1 DB - PRIME DP - Unbound Medicine ER -