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In utero Epstein-Barr virus (infectious mononucleosis) infection.
JAMA. 1981 Oct 02; 246(14):1579-81.JAMA

Abstract

A male infant infected in utero with Epstein-Barr virus (EBV) demonstrated a syndrome of multiple congenital anomalies (micrognathia, cryptorchidism, central cataracts), hypotonia, thrombocytopenia, persistent monocytosis, proteinuria, and multiple areas of metaphysitis at birth. Lymphocytes were Epstein-Barr nuclear antigen (EBNA) positive (18%) and persisted in culture for three months. He had antibody to early antigen (anti-EA), IgM-viral capsid (anti-VCA), and EBNA (anti-EBNA) detectable at 22 days of age. All attempts to isolate infectious agents or to serologically identify other infectious causes for his syndrome were negative.

Authors

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Pub Type(s)

Case Reports
Journal Article

Language

eng

PubMed ID

6268854

Citation

Goldberg, G N., et al. "In Utero Epstein-Barr Virus (infectious Mononucleosis) Infection." JAMA, vol. 246, no. 14, 1981, pp. 1579-81.
Goldberg GN, Fulginiti VA, Ray CG, et al. In utero Epstein-Barr virus (infectious mononucleosis) infection. JAMA. 1981;246(14):1579-81.
Goldberg, G. N., Fulginiti, V. A., Ray, C. G., Ferry, P., Jones, J. F., Cross, H., & Minnich, L. (1981). In utero Epstein-Barr virus (infectious mononucleosis) infection. JAMA, 246(14), 1579-81.
Goldberg GN, et al. In Utero Epstein-Barr Virus (infectious Mononucleosis) Infection. JAMA. 1981 Oct 2;246(14):1579-81. PubMed PMID: 6268854.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - In utero Epstein-Barr virus (infectious mononucleosis) infection. AU - Goldberg,G N, AU - Fulginiti,V A, AU - Ray,C G, AU - Ferry,P, AU - Jones,J F, AU - Cross,H, AU - Minnich,L, PY - 1981/10/2/pubmed PY - 1981/10/2/medline PY - 1981/10/2/entrez SP - 1579 EP - 81 JF - JAMA JO - JAMA VL - 246 IS - 14 N2 - A male infant infected in utero with Epstein-Barr virus (EBV) demonstrated a syndrome of multiple congenital anomalies (micrognathia, cryptorchidism, central cataracts), hypotonia, thrombocytopenia, persistent monocytosis, proteinuria, and multiple areas of metaphysitis at birth. Lymphocytes were Epstein-Barr nuclear antigen (EBNA) positive (18%) and persisted in culture for three months. He had antibody to early antigen (anti-EA), IgM-viral capsid (anti-VCA), and EBNA (anti-EBNA) detectable at 22 days of age. All attempts to isolate infectious agents or to serologically identify other infectious causes for his syndrome were negative. SN - 0098-7484 UR - https://www.unboundmedicine.com/medline/citation/6268854/In_utero_Epstein-Barr_virus_(infectious_mononucleosis)_infection L2 - https://jamanetwork.com/journals/jama/fullarticle/vol/246/pg/1579 DB - PRIME DP - Unbound Medicine ER -