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Effects of various oestrogens on circulating androgens and cortisol during replacement therapy in post-menopausal women.
Maturitas. 1981 Dec; 3(3-4):301-8.M

Abstract

The influence of various oestrogens during unopposed replacement therapy on circulating androgens and cortisol was studied in 65 post-menopausal women. As dose dependent decrease in dehydroepiandrosterone sulphate (DHAS) was found. Ethinyloestradiol (0.05 mg daily) already gave a significant decrease after 1 mth of treatment. The decline following 17 beta-oestradiol (2 mg) and oestrone sulphate (2.5 mg) was less pronounced. Oestriol (6 mg daily) had no effect. Ethinyloestradiol also increased the levels of total cortisol and testosterone, probable because of serum protein induction, while 17 beta-oestradiol had no significant effect. Serum levels of androstenedione remained unchanged during therapy.

Authors

No affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info available

Pub Type(s)

Journal Article
Research Support, Non-U.S. Gov't

Language

eng

PubMed ID

6278266

Citation

Helgason, S, et al. "Effects of Various Oestrogens On Circulating Androgens and Cortisol During Replacement Therapy in Post-menopausal Women." Maturitas, vol. 3, no. 3-4, 1981, pp. 301-8.
Helgason S, Carlström K, Damber MG, et al. Effects of various oestrogens on circulating androgens and cortisol during replacement therapy in post-menopausal women. Maturitas. 1981;3(3-4):301-8.
Helgason, S., Carlström, K., Damber, M. G., Damber, J. E., Selstam, G., & von Schoultz, B. (1981). Effects of various oestrogens on circulating androgens and cortisol during replacement therapy in post-menopausal women. Maturitas, 3(3-4), 301-8.
Helgason S, et al. Effects of Various Oestrogens On Circulating Androgens and Cortisol During Replacement Therapy in Post-menopausal Women. Maturitas. 1981;3(3-4):301-8. PubMed PMID: 6278266.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Effects of various oestrogens on circulating androgens and cortisol during replacement therapy in post-menopausal women. AU - Helgason,S, AU - Carlström,K, AU - Damber,M G, AU - Damber,J E, AU - Selstam,G, AU - von Schoultz,B, PY - 1981/12/1/pubmed PY - 1981/12/1/medline PY - 1981/12/1/entrez SP - 301 EP - 8 JF - Maturitas JO - Maturitas VL - 3 IS - 3-4 N2 - The influence of various oestrogens during unopposed replacement therapy on circulating androgens and cortisol was studied in 65 post-menopausal women. As dose dependent decrease in dehydroepiandrosterone sulphate (DHAS) was found. Ethinyloestradiol (0.05 mg daily) already gave a significant decrease after 1 mth of treatment. The decline following 17 beta-oestradiol (2 mg) and oestrone sulphate (2.5 mg) was less pronounced. Oestriol (6 mg daily) had no effect. Ethinyloestradiol also increased the levels of total cortisol and testosterone, probable because of serum protein induction, while 17 beta-oestradiol had no significant effect. Serum levels of androstenedione remained unchanged during therapy. SN - 0378-5122 UR - https://www.unboundmedicine.com/medline/citation/6278266/Effects_of_various_oestrogens_on_circulating_androgens_and_cortisol_during_replacement_therapy_in_post_menopausal_women_ L2 - https://linkinghub.elsevier.com/retrieve/pii/0378-5122(81)90038-4 DB - PRIME DP - Unbound Medicine ER -