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Spectral character of sunlight modulates photosynthesis of previtamin D3 and its photoisomers in human skin.
Science. 1982 May 28; 216(4549):1001-3.Sci

Abstract

The photosynthesis of previtamin D3 from 7-dehydrocholesterol in human skin was determined after exposure to narrow-band radiation or simulated solar radiation. The optimum wavelengths for the production of previtamin D3 were determined to be between 295 and 300 nanometers. When human skin was exposed to 295-nanometer radiation, up to 65 percent of the original 7-dehydrocholesterol content was converted to previtamin D3. In comparison, when adjacent skin was exposed to simulated solar radiation, the maximum formation of previtamin D3 was about 20 percent. Major differences in the formation of lumisterol3, and tachysterol3 from previtamin D3 were also observed. It is concluded that the spectral character of natural sunlight has a profound effect on the photochemistry of 7-dehydrocholesterol in human skin.

Authors

No affiliation info availableNo affiliation info availableNo affiliation info available

Pub Type(s)

Journal Article
Research Support, Non-U.S. Gov't
Research Support, U.S. Gov't, P.H.S.

Language

eng

PubMed ID

6281884

Citation

MacLaughlin, J A., et al. "Spectral Character of Sunlight Modulates Photosynthesis of Previtamin D3 and Its Photoisomers in Human Skin." Science (New York, N.Y.), vol. 216, no. 4549, 1982, pp. 1001-3.
MacLaughlin JA, Anderson RR, Holick MF. Spectral character of sunlight modulates photosynthesis of previtamin D3 and its photoisomers in human skin. Science. 1982;216(4549):1001-3.
MacLaughlin, J. A., Anderson, R. R., & Holick, M. F. (1982). Spectral character of sunlight modulates photosynthesis of previtamin D3 and its photoisomers in human skin. Science (New York, N.Y.), 216(4549), 1001-3.
MacLaughlin JA, Anderson RR, Holick MF. Spectral Character of Sunlight Modulates Photosynthesis of Previtamin D3 and Its Photoisomers in Human Skin. Science. 1982 May 28;216(4549):1001-3. PubMed PMID: 6281884.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Spectral character of sunlight modulates photosynthesis of previtamin D3 and its photoisomers in human skin. AU - MacLaughlin,J A, AU - Anderson,R R, AU - Holick,M F, PY - 1982/5/28/pubmed PY - 1982/5/28/medline PY - 1982/5/28/entrez SP - 1001 EP - 3 JF - Science (New York, N.Y.) JO - Science VL - 216 IS - 4549 N2 - The photosynthesis of previtamin D3 from 7-dehydrocholesterol in human skin was determined after exposure to narrow-band radiation or simulated solar radiation. The optimum wavelengths for the production of previtamin D3 were determined to be between 295 and 300 nanometers. When human skin was exposed to 295-nanometer radiation, up to 65 percent of the original 7-dehydrocholesterol content was converted to previtamin D3. In comparison, when adjacent skin was exposed to simulated solar radiation, the maximum formation of previtamin D3 was about 20 percent. Major differences in the formation of lumisterol3, and tachysterol3 from previtamin D3 were also observed. It is concluded that the spectral character of natural sunlight has a profound effect on the photochemistry of 7-dehydrocholesterol in human skin. SN - 0036-8075 UR - https://www.unboundmedicine.com/medline/citation/6281884/Spectral_character_of_sunlight_modulates_photosynthesis_of_previtamin_D3_and_its_photoisomers_in_human_skin_ L2 - https://www.sciencemag.org/cgi/pmidlookup?view=long&pmid=6281884 DB - PRIME DP - Unbound Medicine ER -