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[Protection of essential fatty acids by vitamin E].
Acta Vitaminol Enzymol. 1982; 4(3):267-77.AV

Abstract

The protective role of vitamin E against free-radical-mediated oxidations is discussed. In spite of the presence of vitamin E in cell membranes, as structural complex with polyunsaturated fatty acids (PUFA) of phospholipids, the question arises whether high PUFA containing diets, producing high deposition of PUFA in the tissues, can nevertheless lead to peroxidations in the body. It has been suggested that large amounts of dietary PUFA increase the requirement for vitamin E and deplete its tissue stores, particularly when PUFA are discontinued in the diet, also because of their longer half-life time than tocopherols. However, in physiological conditions, linoleic acid up to 10% of caloric intake seems to have no effects on vitamin E requirement. In contrast, in essential fatty acid (EFA) deficient animals, also the addition of small amounts of dietary EFA, by resulting in a proportional increase in PUFA content of membrane structural lipids, is associated with an increased need for vitamin E. This becomes particularly important in the case of dietary fish oils or other poorly protected fats.

Authors

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Pub Type(s)

Comparative Study
English Abstract
Journal Article
Review

Language

ita

PubMed ID

6293292

Citation

Turchetto, E, and C Pignatti. "[Protection of Essential Fatty Acids By Vitamin E]." Acta Vitaminologica Et Enzymologica, vol. 4, no. 3, 1982, pp. 267-77.
Turchetto E, Pignatti C. [Protection of essential fatty acids by vitamin E]. Acta Vitaminol Enzymol. 1982;4(3):267-77.
Turchetto, E., & Pignatti, C. (1982). [Protection of essential fatty acids by vitamin E]. Acta Vitaminologica Et Enzymologica, 4(3), 267-77.
Turchetto E, Pignatti C. [Protection of Essential Fatty Acids By Vitamin E]. Acta Vitaminol Enzymol. 1982;4(3):267-77. PubMed PMID: 6293292.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - [Protection of essential fatty acids by vitamin E]. AU - Turchetto,E, AU - Pignatti,C, PY - 1982/1/1/pubmed PY - 1982/1/1/medline PY - 1982/1/1/entrez SP - 267 EP - 77 JF - Acta vitaminologica et enzymologica JO - Acta Vitaminol Enzymol VL - 4 IS - 3 N2 - The protective role of vitamin E against free-radical-mediated oxidations is discussed. In spite of the presence of vitamin E in cell membranes, as structural complex with polyunsaturated fatty acids (PUFA) of phospholipids, the question arises whether high PUFA containing diets, producing high deposition of PUFA in the tissues, can nevertheless lead to peroxidations in the body. It has been suggested that large amounts of dietary PUFA increase the requirement for vitamin E and deplete its tissue stores, particularly when PUFA are discontinued in the diet, also because of their longer half-life time than tocopherols. However, in physiological conditions, linoleic acid up to 10% of caloric intake seems to have no effects on vitamin E requirement. In contrast, in essential fatty acid (EFA) deficient animals, also the addition of small amounts of dietary EFA, by resulting in a proportional increase in PUFA content of membrane structural lipids, is associated with an increased need for vitamin E. This becomes particularly important in the case of dietary fish oils or other poorly protected fats. SN - 0300-8924 UR - https://www.unboundmedicine.com/medline/citation/6293292/[Protection_of_essential_fatty_acids_by_vitamin_E]_ L2 - https://medlineplus.gov/vitamine.html DB - PRIME DP - Unbound Medicine ER -