Tags

Type your tag names separated by a space and hit enter

Correlation between gallium lung scans and fiberoptic bronchoscopy in patients with suspected Pneumocystis carinii pneumonia and the acquired immune deficiency syndrome.
Am Rev Respir Dis. 1984 Dec; 130(6):1166-9.AR

Abstract

We retrospectively examined the sensitivity and specificity of gallium lung scans for detecting Pneumocystis carinii pneumonia in 22 patients with known or suspected acquired immune deficiency syndrome. Correlations were made between bronchoscopic results and gallium scan findings interpreted using a simple system (normal or abnormal) and a graded score (1 to 4). All 12 patients with Pneumocystis had abnormal scans by both interpretations (sensitivity, 100%). Five of these 12 patients had normal arterial PO2 values, chest roentgenograms, or both. In the 10 patients without Pneumocystis, scans were read as abnormal in 8 using the simple system (specificity, 20%) but were abnormal in only 1 using the grading system (specificity, 90%). Five patients with Pneumocystis pneumonia had scans and bronchoscopy after treatment; neither method of interpretation correlated with the presence of organisms. We conclude: (1) gallium scanning is a sensitive initial diagnostic test in patients with suspected Pneumocystis pneumonia; (2) a graded scoring system improves specificity; (3) an abnormal gallium scan (3 or greater) in patients with suspected Pneumocystis pneumonia is an indication for biopsy, even when the PO2 and/or chest roentgenogram are normal.

Links

Publisher Full Text

Authors

Coleman DL
No affiliation info available
Hattner RS
No affiliation info available
Luce JM
No affiliation info available
Dodek PM
No affiliation info available
Golden JA
No affiliation info available
Murray JF
No affiliation info available

MeSH

Acquired Immunodeficiency SyndromeAdultBronchoscopyFiber Optic TechnologyFollow-Up StudiesGallium RadioisotopesHumansLungMalePneumonia, PneumocystisRadiographyRetrospective Studies

Pub Type(s)

Journal Article
Research Support, U.S. Gov't, P.H.S.

Language

eng

PubMed ID

6334463

Citation

Coleman, D L., et al. "Correlation Between Gallium Lung Scans and Fiberoptic Bronchoscopy in Patients With Suspected Pneumocystis Carinii Pneumonia and the Acquired Immune Deficiency Syndrome." The American Review of Respiratory Disease, vol. 130, no. 6, 1984, pp. 1166-9.
Coleman DL, Hattner RS, Luce JM, et al. Correlation between gallium lung scans and fiberoptic bronchoscopy in patients with suspected Pneumocystis carinii pneumonia and the acquired immune deficiency syndrome. Am Rev Respir Dis. 1984;130(6):1166-9.
Coleman, D. L., Hattner, R. S., Luce, J. M., Dodek, P. M., Golden, J. A., & Murray, J. F. (1984). Correlation between gallium lung scans and fiberoptic bronchoscopy in patients with suspected Pneumocystis carinii pneumonia and the acquired immune deficiency syndrome. The American Review of Respiratory Disease, 130(6), 1166-9.
Coleman DL, et al. Correlation Between Gallium Lung Scans and Fiberoptic Bronchoscopy in Patients With Suspected Pneumocystis Carinii Pneumonia and the Acquired Immune Deficiency Syndrome. Am Rev Respir Dis. 1984;130(6):1166-9. PubMed PMID: 6334463.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Correlation between gallium lung scans and fiberoptic bronchoscopy in patients with suspected Pneumocystis carinii pneumonia and the acquired immune deficiency syndrome. AU - Coleman,D L, AU - Hattner,R S, AU - Luce,J M, AU - Dodek,P M, AU - Golden,J A, AU - Murray,J F, PY - 1984/12/1/pubmed PY - 1984/12/1/medline PY - 1984/12/1/entrez SP - 1166 EP - 9 JF - The American review of respiratory disease JO - Am Rev Respir Dis VL - 130 IS - 6 N2 - We retrospectively examined the sensitivity and specificity of gallium lung scans for detecting Pneumocystis carinii pneumonia in 22 patients with known or suspected acquired immune deficiency syndrome. Correlations were made between bronchoscopic results and gallium scan findings interpreted using a simple system (normal or abnormal) and a graded score (1 to 4). All 12 patients with Pneumocystis had abnormal scans by both interpretations (sensitivity, 100%). Five of these 12 patients had normal arterial PO2 values, chest roentgenograms, or both. In the 10 patients without Pneumocystis, scans were read as abnormal in 8 using the simple system (specificity, 20%) but were abnormal in only 1 using the grading system (specificity, 90%). Five patients with Pneumocystis pneumonia had scans and bronchoscopy after treatment; neither method of interpretation correlated with the presence of organisms. We conclude: (1) gallium scanning is a sensitive initial diagnostic test in patients with suspected Pneumocystis pneumonia; (2) a graded scoring system improves specificity; (3) an abnormal gallium scan (3 or greater) in patients with suspected Pneumocystis pneumonia is an indication for biopsy, even when the PO2 and/or chest roentgenogram are normal. SN - 0003-0805 UR - https://www.unboundmedicine.com/medline/citation/6334463/Correlation_between_gallium_lung_scans_and_fiberoptic_bronchoscopy_in_patients_with_suspected_Pneumocystis_carinii_pneumonia_and_the_acquired_immune_deficiency_syndrome_ L2 - https://www.atsjournals.org/doi/10.1164/arrd.1984.130.6.1166?url_ver=Z39.88-2003&rfr_id=ori:rid:crossref.org&rfr_dat=cr_pub=pubmed DB - PRIME DP - Unbound Medicine ER -