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Replication of pBR322 DNA in stringent and relaxed strains of Escherichia coli.
Mol Gen Genet. 1983; 190(2):355-7.MG

Abstract

Synthesis of both chromosomal and plasmid (pBR322) DNA was measured in E. coli strains differing in their relA allele (relA+:CP78; relA:CP79). It was found that upon limitation of a required amino acid or after valine treatment to trigger a stringent response synthesis of pBR322 DNA was stimulated only in the relaxed strain and was inhibited in its stringent counterpart. The results suggest that replication of plasmid DNA is negatively controlled by the relA+ allele.

Authors

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Pub Type(s)

Journal Article

Language

eng

PubMed ID

6348477

Citation

Hecker, M, et al. "Replication of pBR322 DNA in Stringent and Relaxed Strains of Escherichia Coli." Molecular & General Genetics : MGG, vol. 190, no. 2, 1983, pp. 355-7.
Hecker M, Schroeter A, Mach F. Replication of pBR322 DNA in stringent and relaxed strains of Escherichia coli. Mol Gen Genet. 1983;190(2):355-7.
Hecker, M., Schroeter, A., & Mach, F. (1983). Replication of pBR322 DNA in stringent and relaxed strains of Escherichia coli. Molecular & General Genetics : MGG, 190(2), 355-7.
Hecker M, Schroeter A, Mach F. Replication of pBR322 DNA in Stringent and Relaxed Strains of Escherichia Coli. Mol Gen Genet. 1983;190(2):355-7. PubMed PMID: 6348477.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Replication of pBR322 DNA in stringent and relaxed strains of Escherichia coli. AU - Hecker,M, AU - Schroeter,A, AU - Mach,F, PY - 1983/1/1/pubmed PY - 1983/1/1/medline PY - 1983/1/1/entrez SP - 355 EP - 7 JF - Molecular & general genetics : MGG JO - Mol. Gen. Genet. VL - 190 IS - 2 N2 - Synthesis of both chromosomal and plasmid (pBR322) DNA was measured in E. coli strains differing in their relA allele (relA+:CP78; relA:CP79). It was found that upon limitation of a required amino acid or after valine treatment to trigger a stringent response synthesis of pBR322 DNA was stimulated only in the relaxed strain and was inhibited in its stringent counterpart. The results suggest that replication of plasmid DNA is negatively controlled by the relA+ allele. SN - 0026-8925 UR - https://www.unboundmedicine.com/medline/citation/6348477/Replication_of_pBR322_DNA_in_stringent_and_relaxed_strains_of_Escherichia_coli_ DB - PRIME DP - Unbound Medicine ER -