Tags

Type your tag names separated by a space and hit enter

Parietal cell autoantibodies: localization of their binding sites on isolated gastric glands.
Clin Exp Immunol. 1983 Aug; 53(2):406-12.CE

Abstract

The localization of antigens reacting with parietal cell antibodies found in the sera of some patients with pernicious anaemia was studied by the indirect immunoperoxidase method on viable gastric glands isolated from the mouse or human fundus by collagenase digestion. We observed that only the luminal surface of parietal cell bound antibodies, whereas their lateral and basal surfaces were not stained. From this data it is concluded that parietal cell antibodies are unlikely to be cytotoxic in vivo.

Links

PMC Free PDF
PMC Free Full Text

Authors

Duchateau A
No affiliation info available
Zeitoun P
No affiliation info available

MeSH

AnimalsAntigens, SurfaceAutoantibodiesBinding Sites, AntibodyCell MembraneFluorescent Antibody TechniqueGastric FundusGastric MucosaHumansImmunoenzyme TechniquesMice

Pub Type(s)

Journal Article
Research Support, Non-U.S. Gov't

Language

eng

PubMed ID

6349880

Citation

Duchateau, A, and P Zeitoun. "Parietal Cell Autoantibodies: Localization of Their Binding Sites On Isolated Gastric Glands." Clinical and Experimental Immunology, vol. 53, no. 2, 1983, pp. 406-12.
Duchateau A, Zeitoun P. Parietal cell autoantibodies: localization of their binding sites on isolated gastric glands. Clin Exp Immunol. 1983;53(2):406-12.
Duchateau, A., & Zeitoun, P. (1983). Parietal cell autoantibodies: localization of their binding sites on isolated gastric glands. Clinical and Experimental Immunology, 53(2), 406-12.
Duchateau A, Zeitoun P. Parietal Cell Autoantibodies: Localization of Their Binding Sites On Isolated Gastric Glands. Clin Exp Immunol. 1983;53(2):406-12. PubMed PMID: 6349880.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Parietal cell autoantibodies: localization of their binding sites on isolated gastric glands. AU - Duchateau,A, AU - Zeitoun,P, PY - 1983/8/1/pubmed PY - 1983/8/1/medline PY - 1983/8/1/entrez SP - 406 EP - 12 JF - Clinical and experimental immunology JO - Clin Exp Immunol VL - 53 IS - 2 N2 - The localization of antigens reacting with parietal cell antibodies found in the sera of some patients with pernicious anaemia was studied by the indirect immunoperoxidase method on viable gastric glands isolated from the mouse or human fundus by collagenase digestion. We observed that only the luminal surface of parietal cell bound antibodies, whereas their lateral and basal surfaces were not stained. From this data it is concluded that parietal cell antibodies are unlikely to be cytotoxic in vivo. SN - 0009-9104 UR - https://www.unboundmedicine.com/medline/citation/6349880/Parietal_cell_autoantibodies:_localization_of_their_binding_sites_on_isolated_gastric_glands_ L2 - https://www.ncbi.nlm.nih.gov/pmc/articles/pmid/6349880/ DB - PRIME DP - Unbound Medicine ER -