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Leprosy in wild armadillos (Dasypus novemcinctus) on the Texas Gulf Coast. Ultrastructure of the liver and spleen.
Lab Invest. 1983 Sep; 49(3):281-90.LI

Abstract

Recent studies have established that the "naturally-occurring leprosy-like disease of wild armadillos" is, indeed, caused by Mycobacterium leprae indistinguishable from M. leprae from human lepromatous leprosy. The present study reports the ultrastructure of the mycobacteria and host response in deep viscera, liver and spleen, in Texas armadillos with sylvatic leprosy. Evidence for acid-fast bacillary proliferation in these organs and penetration of hepatocytes is given. Acid-fast bacilli concentrated in activated macrophages in Billroth cords and sheaths of Schweigger-Seidel of the spleen and in Kupffer cells of the liver. Both mycobacteria and host response seen in lepromata of sylvatic leprosy, lepromatous lesions produced by injection of inocula from human lepromata and human lepromata, are compared.

Authors

No affiliation info availableNo affiliation info availableNo affiliation info available

Pub Type(s)

Journal Article
Research Support, Non-U.S. Gov't

Language

eng

PubMed ID

6350703

Citation

Meier, J L., et al. "Leprosy in Wild Armadillos (Dasypus Novemcinctus) On the Texas Gulf Coast. Ultrastructure of the Liver and Spleen." Laboratory Investigation; a Journal of Technical Methods and Pathology, vol. 49, no. 3, 1983, pp. 281-90.
Meier JL, Folse DS, Smith JH. Leprosy in wild armadillos (Dasypus novemcinctus) on the Texas Gulf Coast. Ultrastructure of the liver and spleen. Lab Invest. 1983;49(3):281-90.
Meier, J. L., Folse, D. S., & Smith, J. H. (1983). Leprosy in wild armadillos (Dasypus novemcinctus) on the Texas Gulf Coast. Ultrastructure of the liver and spleen. Laboratory Investigation; a Journal of Technical Methods and Pathology, 49(3), 281-90.
Meier JL, Folse DS, Smith JH. Leprosy in Wild Armadillos (Dasypus Novemcinctus) On the Texas Gulf Coast. Ultrastructure of the Liver and Spleen. Lab Invest. 1983;49(3):281-90. PubMed PMID: 6350703.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Leprosy in wild armadillos (Dasypus novemcinctus) on the Texas Gulf Coast. Ultrastructure of the liver and spleen. AU - Meier,J L, AU - Folse,D S, AU - Smith,J H, PY - 1983/9/1/pubmed PY - 1983/9/1/medline PY - 1983/9/1/entrez SP - 281 EP - 90 JF - Laboratory investigation; a journal of technical methods and pathology JO - Lab Invest VL - 49 IS - 3 N2 - Recent studies have established that the "naturally-occurring leprosy-like disease of wild armadillos" is, indeed, caused by Mycobacterium leprae indistinguishable from M. leprae from human lepromatous leprosy. The present study reports the ultrastructure of the mycobacteria and host response in deep viscera, liver and spleen, in Texas armadillos with sylvatic leprosy. Evidence for acid-fast bacillary proliferation in these organs and penetration of hepatocytes is given. Acid-fast bacilli concentrated in activated macrophages in Billroth cords and sheaths of Schweigger-Seidel of the spleen and in Kupffer cells of the liver. Both mycobacteria and host response seen in lepromata of sylvatic leprosy, lepromatous lesions produced by injection of inocula from human lepromata and human lepromata, are compared. SN - 0023-6837 UR - https://www.unboundmedicine.com/medline/citation/6350703/Leprosy_in_wild_armadillos__Dasypus_novemcinctus__on_the_Texas_Gulf_Coast__Ultrastructure_of_the_liver_and_spleen_ L2 - https://medlineplus.gov/mycobacterialinfections.html DB - PRIME DP - Unbound Medicine ER -