Stimulation of vessel wall prostacyclin by selective thromboxane synthetase inhibitor OKY 1581.Prostaglandins Leukot Med 1983; 12(1):49-52PL
Abstract
Human umbilical veins have been shown to produce small amounts of TXA2 in addition to PGI2. We measured relative TXA2 and PGI2 production by umbilical veins in the presence of selective TXA2 synthetase inhibitor OKY 1581. OKY 1581 treatment resulted in inhibition of TXA2 but a marked increase in PGI2 release, which may relate to diversion of cyclic endoperoxides to PGI2 pathway or to removal of a feedback control at the level of AA mobilization.
MeSH
Pub Type(s)
Journal Article
Language
eng
PubMed ID
6356153
Citation
Mehta, J, et al. "Stimulation of Vessel Wall Prostacyclin By Selective Thromboxane Synthetase Inhibitor OKY 1581." Prostaglandins, Leukotrienes, and Medicine, vol. 12, no. 1, 1983, pp. 49-52.
Mehta J, Mehta P, Ostrowski N. Stimulation of vessel wall prostacyclin by selective thromboxane synthetase inhibitor OKY 1581. Prostaglandins Leukot Med. 1983;12(1):49-52.
Mehta, J., Mehta, P., & Ostrowski, N. (1983). Stimulation of vessel wall prostacyclin by selective thromboxane synthetase inhibitor OKY 1581. Prostaglandins, Leukotrienes, and Medicine, 12(1), pp. 49-52.
Mehta J, Mehta P, Ostrowski N. Stimulation of Vessel Wall Prostacyclin By Selective Thromboxane Synthetase Inhibitor OKY 1581. Prostaglandins Leukot Med. 1983;12(1):49-52. PubMed PMID: 6356153.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR
T1 - Stimulation of vessel wall prostacyclin by selective thromboxane synthetase inhibitor OKY 1581.
AU - Mehta,J,
AU - Mehta,P,
AU - Ostrowski,N,
PY - 1983/9/1/pubmed
PY - 1983/9/1/medline
PY - 1983/9/1/entrez
SP - 49
EP - 52
JF - Prostaglandins, leukotrienes, and medicine
JO - Prostaglandins Leukot Med
VL - 12
IS - 1
N2 - Human umbilical veins have been shown to produce small amounts of TXA2 in addition to PGI2. We measured relative TXA2 and PGI2 production by umbilical veins in the presence of selective TXA2 synthetase inhibitor OKY 1581. OKY 1581 treatment resulted in inhibition of TXA2 but a marked increase in PGI2 release, which may relate to diversion of cyclic endoperoxides to PGI2 pathway or to removal of a feedback control at the level of AA mobilization.
SN - 0262-1746
UR - https://www.unboundmedicine.com/medline/citation/6356153/Stimulation_of_vessel_wall_prostacyclin_by_selective_thromboxane_synthetase_inhibitor_OKY_1581_
DB - PRIME
DP - Unbound Medicine
ER -
