Abstract
The meaning of eradication, which is an irreversible conclusion, is considered primarily to distinguish it from elimination, which is reversible from outside the area. Poliomyelitis and measles are at present the diseases for which conditions most favor an attempt to produce eradication. Poliomyelitis has now reached a frequency in the developing world as high as it was in the prevaccine era of the United States. The use of oral vaccine is a deliberate attempt to substitute the wild-type polioviruses in the community with the vaccine-like viruses derived from the vaccine itself. Mass use of vaccine in all children less than five years of age on a single day twice in a year has produced a critical decrease in the incidence of the disease in Brazil. Following determined efforts to achieve immunization of at least 95% of the population, the United States is now nearing the state of complete freedom from the transmission of measles virus. The use of diploid cells for making vaccine has enabled the virus to be given as an aerosol to babies less than six months of age and would be of particular value in developing countries. The high transmissibility of measles makes a severe demand for vaccine, but so long as the uptake of vaccine reaches at least 90%, the successful elimination of measles is extremely probable.
TY - JOUR
T1 - Prospects for the eradication of infectious diseases.
A1 - Stuart-Harris,C,
PY - 1984/5/1/pubmed
PY - 1984/5/1/medline
PY - 1984/5/1/entrez
KW - Bacterial And Fungal Diseases
KW - Biological Characteristics
KW - Biology
KW - Communicable Disease Control
KW - Communicable Diseases
KW - Delivery Of Health Care
KW - Developing Countries
KW - Diseases
KW - Health
KW - Health Services
KW - Health Services Administration
KW - Immunization
KW - Infections
KW - Management
KW - Medicine
KW - Organization And Administration
KW - Physiology
KW - Preventive Medicine
KW - Primary Health Care
KW - Public Health
KW - Vaccination
KW - Viral Diseases
SP - 405
EP - 11
JF - Reviews of infectious diseases
JO - Rev. Infect. Dis.
VL - 6
IS - 3
N2 - The meaning of eradication, which is an irreversible conclusion, is considered primarily to distinguish it from elimination, which is reversible from outside the area. Poliomyelitis and measles are at present the diseases for which conditions most favor an attempt to produce eradication. Poliomyelitis has now reached a frequency in the developing world as high as it was in the prevaccine era of the United States. The use of oral vaccine is a deliberate attempt to substitute the wild-type polioviruses in the community with the vaccine-like viruses derived from the vaccine itself. Mass use of vaccine in all children less than five years of age on a single day twice in a year has produced a critical decrease in the incidence of the disease in Brazil. Following determined efforts to achieve immunization of at least 95% of the population, the United States is now nearing the state of complete freedom from the transmission of measles virus. The use of diploid cells for making vaccine has enabled the virus to be given as an aerosol to babies less than six months of age and would be of particular value in developing countries. The high transmissibility of measles makes a severe demand for vaccine, but so long as the uptake of vaccine reaches at least 90%, the successful elimination of measles is extremely probable.
SN - 0162-0886
UR - https://www.unboundmedicine.com/medline/citation/6377445/Prospects_for_the_eradication_of_infectious_diseases_
L2 - https://medlineplus.gov/measles.html
DB - PRIME
DP - Unbound Medicine
ER -
