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Purified chick embryo cell (PCEC) rabies vaccine for human use: clinical trials.
Behring Inst Mitt. 1984 NovBI

Abstract

The purpose of the study was the clinical evaluation of the new PCEC-Rabies-Vaccine. In 620 healthy volunteers mild local side-reactions could be observed in less than 2% of the vaccinations. No relevant general reactions have been reported or seen after the 2200 injections apart three cases of urticaria. All the 218 volunteers tested developed neutralising rabies antibodies of the IgG-type between day 0 and day 30 after the first vaccination dose. In 45 patients the PCEC-Rabies-Vaccine, applied together with human rabies immunoglobulin in a postexposure vaccination, afforded protection against rabies after contact with a proven rabid animal. The clinical trials are proof that the compatibility and efficacy of the PCEC-Rabies-Vaccine match the high standards established by the HDC-Rabies-Vaccine.

Authors

No affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info available

Pub Type(s)

Clinical Trial
Comparative Study
Journal Article

Language

eng

PubMed ID

6395850

Citation

Bijok, U, et al. "Purified Chick Embryo Cell (PCEC) Rabies Vaccine for Human Use: Clinical Trials." Behring Institute Mitteilungen, 1984, pp. 155-64.
Bijok U, Vodopija I, Smerdel S, et al. Purified chick embryo cell (PCEC) rabies vaccine for human use: clinical trials. Behring Inst Mitt. 1984.
Bijok, U., Vodopija, I., Smerdel, S., Thongcharoen, P., Nicholson, K., Dietrich, M., & Gonzalez de Cosio, A. (1984). Purified chick embryo cell (PCEC) rabies vaccine for human use: clinical trials. Behring Institute Mitteilungen, (76), 155-64.
Bijok U, et al. Purified Chick Embryo Cell (PCEC) Rabies Vaccine for Human Use: Clinical Trials. Behring Inst Mitt. 1984;(76)155-64. PubMed PMID: 6395850.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Purified chick embryo cell (PCEC) rabies vaccine for human use: clinical trials. AU - Bijok,U, AU - Vodopija,I, AU - Smerdel,S, AU - Thongcharoen,P, AU - Nicholson,K, AU - Dietrich,M, AU - Gonzalez de Cosio,A, PY - 1984/11/1/pubmed PY - 1984/11/1/medline PY - 1984/11/1/entrez SP - 155 EP - 64 JF - Behring Institute Mitteilungen JO - Behring Inst Mitt IS - 76 N2 - The purpose of the study was the clinical evaluation of the new PCEC-Rabies-Vaccine. In 620 healthy volunteers mild local side-reactions could be observed in less than 2% of the vaccinations. No relevant general reactions have been reported or seen after the 2200 injections apart three cases of urticaria. All the 218 volunteers tested developed neutralising rabies antibodies of the IgG-type between day 0 and day 30 after the first vaccination dose. In 45 patients the PCEC-Rabies-Vaccine, applied together with human rabies immunoglobulin in a postexposure vaccination, afforded protection against rabies after contact with a proven rabid animal. The clinical trials are proof that the compatibility and efficacy of the PCEC-Rabies-Vaccine match the high standards established by the HDC-Rabies-Vaccine. SN - 0301-0457 UR - https://www.unboundmedicine.com/medline/citation/6395850/Purified_chick_embryo_cell__PCEC__rabies_vaccine_for_human_use:_clinical_trials_ L2 - http://www.diseaseinfosearch.org/result/6131 DB - PRIME DP - Unbound Medicine ER -