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Serum immunoglobulins and complement (C'3) in oral lichen planus.
Oral Surg Oral Med Oral Pathol. 1983 Jan; 55(1):47-51.OS

Abstract

Serum immunoglobulins and complement (C'3) were determined by single radial immunodiffusion according to the method of Mancini and co-workers in fifty patients with oral lichen planus and twenty persons with clinically normal oral mucosa. Significantly increased levels of serum IgG (p less than 0.05) and a significant reduction of serum IgA concentration (p less than 0.05) in the experimental group as compared with normal controls were observed. Mean serum IgM and complement (C'3) levels were similar in patients and controls. No correlation between disease variety or extensiveness and immunoglobulin or complement levels was noticed. These results suggest that patients with oral lichen planus may have a generalized immunologic disorder in which humoral immunity is disturbed. Whether humoral immunity is of etiologic significance, contributes to the disease process, or, finally, represents an event secondary to the pathologic changes seen in the disease remains to be determined.

Authors

No affiliation info availableNo affiliation info availableNo affiliation info available

Pub Type(s)

Journal Article

Language

eng

PubMed ID

6402750

Citation

Sklavounou, A D., et al. "Serum Immunoglobulins and Complement (C'3) in Oral Lichen Planus." Oral Surgery, Oral Medicine, and Oral Pathology, vol. 55, no. 1, 1983, pp. 47-51.
Sklavounou AD, Laskaris G, Angelopoulos AP. Serum immunoglobulins and complement (C'3) in oral lichen planus. Oral Surg Oral Med Oral Pathol. 1983;55(1):47-51.
Sklavounou, A. D., Laskaris, G., & Angelopoulos, A. P. (1983). Serum immunoglobulins and complement (C'3) in oral lichen planus. Oral Surgery, Oral Medicine, and Oral Pathology, 55(1), 47-51.
Sklavounou AD, Laskaris G, Angelopoulos AP. Serum Immunoglobulins and Complement (C'3) in Oral Lichen Planus. Oral Surg Oral Med Oral Pathol. 1983;55(1):47-51. PubMed PMID: 6402750.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Serum immunoglobulins and complement (C'3) in oral lichen planus. AU - Sklavounou,A D, AU - Laskaris,G, AU - Angelopoulos,A P, PY - 1983/1/1/pubmed PY - 1983/1/1/medline PY - 1983/1/1/entrez SP - 47 EP - 51 JF - Oral surgery, oral medicine, and oral pathology JO - Oral Surg. Oral Med. Oral Pathol. VL - 55 IS - 1 N2 - Serum immunoglobulins and complement (C'3) were determined by single radial immunodiffusion according to the method of Mancini and co-workers in fifty patients with oral lichen planus and twenty persons with clinically normal oral mucosa. Significantly increased levels of serum IgG (p less than 0.05) and a significant reduction of serum IgA concentration (p less than 0.05) in the experimental group as compared with normal controls were observed. Mean serum IgM and complement (C'3) levels were similar in patients and controls. No correlation between disease variety or extensiveness and immunoglobulin or complement levels was noticed. These results suggest that patients with oral lichen planus may have a generalized immunologic disorder in which humoral immunity is disturbed. Whether humoral immunity is of etiologic significance, contributes to the disease process, or, finally, represents an event secondary to the pathologic changes seen in the disease remains to be determined. SN - 0030-4220 UR - https://www.unboundmedicine.com/medline/citation/6402750/Serum_immunoglobulins_and_complement__C'3__in_oral_lichen_planus_ L2 - http://www.diseaseinfosearch.org/result/5399 DB - PRIME DP - Unbound Medicine ER -