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Hormonal consequences of missing the pill during the first two days of three consecutive artificial cycles.
Contraception. 1984 May; 29(5):437-46.C

Abstract

The hormonal effects of the deliberate omission of a low-dose combined oral contraceptive pill (30 micrograms ethinyl estradiol + 150 micrograms levonorgestrel) during the first two days of three consecutive artificial cycles were studied in 10 women. The plasma levels of estradiol, progesterone, levonorgestrel and--whenever justified--of LH were measured three times weekly (Mondays, Wednesdays and Fridays) throughout a 90-day period, and the ovarian reaction to the prolongation of the pill-free period from 7 to 9 days was assessed. One subject (with a premature LH surge) showed a marked follicular and an inadequate luteal activity in 2 of 3 cycles. The remaining cycles were characterized by a varying degree of follicular activity associated with the absence of any luteal function. None of the subjects exhibited peripheral steroid levels indicating a normal ovulatory cycle. The results are interpreted as suggesting that repeated prolongation of the pill-free period from 7 to 9 days might result in a gradual increase in ovarian activity.

Authors

No affiliation info availableNo affiliation info available

Pub Type(s)

Journal Article
Research Support, Non-U.S. Gov't

Language

eng

PubMed ID

6430642

Citation

Landgren, B M., and E Diczfalusy. "Hormonal Consequences of Missing the Pill During the First Two Days of Three Consecutive Artificial Cycles." Contraception, vol. 29, no. 5, 1984, pp. 437-46.
Landgren BM, Diczfalusy E. Hormonal consequences of missing the pill during the first two days of three consecutive artificial cycles. Contraception. 1984;29(5):437-46.
Landgren, B. M., & Diczfalusy, E. (1984). Hormonal consequences of missing the pill during the first two days of three consecutive artificial cycles. Contraception, 29(5), 437-46.
Landgren BM, Diczfalusy E. Hormonal Consequences of Missing the Pill During the First Two Days of Three Consecutive Artificial Cycles. Contraception. 1984;29(5):437-46. PubMed PMID: 6430642.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Hormonal consequences of missing the pill during the first two days of three consecutive artificial cycles. AU - Landgren,B M, AU - Diczfalusy,E, PY - 1984/5/1/pubmed PY - 1984/5/1/medline PY - 1984/5/1/entrez KW - Biology KW - Contraception KW - Contraceptive Agents KW - Contraceptive Agents, Female KW - Contraceptive Agents, Progestin--analysis KW - Contraceptive Agents--analysis KW - Contraceptive Methods KW - Endocrine System KW - Estradiol--analysis KW - Estrogens KW - Ethinyl Estradiol KW - Examinations And Diagnoses KW - Family Planning KW - Gonadotropins KW - Gonadotropins, Pituitary KW - Hormones KW - Laboratory Examinations And Diagnoses KW - Laboratory Procedures KW - Levonorgestrel--analysis KW - Luteinizing Hormone--analysis KW - Oral Contraceptives KW - Oral Contraceptives, Low-dose KW - Physiology KW - Progestational Hormones KW - Progesterone--analysis KW - Reproductive Control Agents SP - 437 EP - 46 JF - Contraception JO - Contraception VL - 29 IS - 5 N2 - The hormonal effects of the deliberate omission of a low-dose combined oral contraceptive pill (30 micrograms ethinyl estradiol + 150 micrograms levonorgestrel) during the first two days of three consecutive artificial cycles were studied in 10 women. The plasma levels of estradiol, progesterone, levonorgestrel and--whenever justified--of LH were measured three times weekly (Mondays, Wednesdays and Fridays) throughout a 90-day period, and the ovarian reaction to the prolongation of the pill-free period from 7 to 9 days was assessed. One subject (with a premature LH surge) showed a marked follicular and an inadequate luteal activity in 2 of 3 cycles. The remaining cycles were characterized by a varying degree of follicular activity associated with the absence of any luteal function. None of the subjects exhibited peripheral steroid levels indicating a normal ovulatory cycle. The results are interpreted as suggesting that repeated prolongation of the pill-free period from 7 to 9 days might result in a gradual increase in ovarian activity. SN - 0010-7824 UR - https://www.unboundmedicine.com/medline/citation/6430642/Hormonal_consequences_of_missing_the_pill_during_the_first_two_days_of_three_consecutive_artificial_cycles_ L2 - https://linkinghub.elsevier.com/retrieve/pii/0010-7824(84)90017-9 DB - PRIME DP - Unbound Medicine ER -