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Bioartificial pancreas. Present state and future prospects.
Biomed Biochim Acta. 1984; 43(5):569-76.BB

Abstract

The bioartificial (hybrid) pancreas separates transplanted tissue (i.e. islets of Langerhans) from the diabetic host and thus protects it against immune rejection. The membranes employed in such devices must be impermeable for immunocytes and immunoglobulins but--due to the particular construction of the devices--more or less selectively permeable for glucose and insulin. A short survey is presented on different systems from the viewpoint of the transport functions realized, i.e. diffusion systems, ultrafiltration systems, and combined diffusion-ultrafiltration systems. All these devices are still in a developmental stage.

Authors

No affiliation info available

Pub Type(s)

Comparative Study
Journal Article

Language

eng

PubMed ID

6433904

Citation

Reach, G. "Bioartificial Pancreas. Present State and Future Prospects." Biomedica Biochimica Acta, vol. 43, no. 5, 1984, pp. 569-76.
Reach G. Bioartificial pancreas. Present state and future prospects. Biomed Biochim Acta. 1984;43(5):569-76.
Reach, G. (1984). Bioartificial pancreas. Present state and future prospects. Biomedica Biochimica Acta, 43(5), 569-76.
Reach G. Bioartificial Pancreas. Present State and Future Prospects. Biomed Biochim Acta. 1984;43(5):569-76. PubMed PMID: 6433904.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Bioartificial pancreas. Present state and future prospects. A1 - Reach,G, PY - 1984/1/1/pubmed PY - 1984/1/1/medline PY - 1984/1/1/entrez SP - 569 EP - 76 JF - Biomedica biochimica acta JO - Biomed Biochim Acta VL - 43 IS - 5 N2 - The bioartificial (hybrid) pancreas separates transplanted tissue (i.e. islets of Langerhans) from the diabetic host and thus protects it against immune rejection. The membranes employed in such devices must be impermeable for immunocytes and immunoglobulins but--due to the particular construction of the devices--more or less selectively permeable for glucose and insulin. A short survey is presented on different systems from the viewpoint of the transport functions realized, i.e. diffusion systems, ultrafiltration systems, and combined diffusion-ultrafiltration systems. All these devices are still in a developmental stage. SN - 0232-766X UR - https://www.unboundmedicine.com/medline/citation/6433904/Bioartificial_pancreas__Present_state_and_future_prospects_ L2 - https://medlineplus.gov/isletcelltransplantation.html DB - PRIME DP - Unbound Medicine ER -