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Nystagmus in motor neuron disease: clinicopathological study of two cases.
Ann Neurol 1984; 16(1):71-7AN

Abstract

Two patients with amyotrophic lateral sclerosis proved postmortem had nystagmus in addition to typical clinical signs of motor neuron disease. The first patient had gaze-evoked rotatory nystagmus that was followed by horizontal nystagmus in the primary position with supranuclear paresis of horizontal gaze and upgaze. The second patient had rotatory nystagmus that was evoked by lateral gaze, with normal range of eye movements. Nystagmus is so rare in motor neuron disease that these observations may imply another disease, but postmortem examination did not provide any other explanation. These two cases add to the increasing evidence that motor neuron disease comprises a heterogeneous group of disorders.

Authors

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Pub Type(s)

Case Reports
Journal Article
Research Support, Non-U.S. Gov't
Research Support, U.S. Gov't, P.H.S.

Language

eng

PubMed ID

6465863

Citation

Kushner, M J., et al. "Nystagmus in Motor Neuron Disease: Clinicopathological Study of Two Cases." Annals of Neurology, vol. 16, no. 1, 1984, pp. 71-7.
Kushner MJ, Parrish M, Burke A, et al. Nystagmus in motor neuron disease: clinicopathological study of two cases. Ann Neurol. 1984;16(1):71-7.
Kushner, M. J., Parrish, M., Burke, A., Behrens, M., Hays, A. P., Frame, B., & Rowland, L. P. (1984). Nystagmus in motor neuron disease: clinicopathological study of two cases. Annals of Neurology, 16(1), pp. 71-7.
Kushner MJ, et al. Nystagmus in Motor Neuron Disease: Clinicopathological Study of Two Cases. Ann Neurol. 1984;16(1):71-7. PubMed PMID: 6465863.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Nystagmus in motor neuron disease: clinicopathological study of two cases. AU - Kushner,M J, AU - Parrish,M, AU - Burke,A, AU - Behrens,M, AU - Hays,A P, AU - Frame,B, AU - Rowland,L P, PY - 1984/7/1/pubmed PY - 1984/7/1/medline PY - 1984/7/1/entrez SP - 71 EP - 7 JF - Annals of neurology JO - Ann. Neurol. VL - 16 IS - 1 N2 - Two patients with amyotrophic lateral sclerosis proved postmortem had nystagmus in addition to typical clinical signs of motor neuron disease. The first patient had gaze-evoked rotatory nystagmus that was followed by horizontal nystagmus in the primary position with supranuclear paresis of horizontal gaze and upgaze. The second patient had rotatory nystagmus that was evoked by lateral gaze, with normal range of eye movements. Nystagmus is so rare in motor neuron disease that these observations may imply another disease, but postmortem examination did not provide any other explanation. These two cases add to the increasing evidence that motor neuron disease comprises a heterogeneous group of disorders. SN - 0364-5134 UR - https://www.unboundmedicine.com/medline/citation/6465863/Nystagmus_in_motor_neuron_disease:_clinicopathological_study_of_two_cases_ L2 - https://onlinelibrary.wiley.com/resolve/openurl?genre=article&sid=nlm:pubmed&issn=0364-5134&date=1984&volume=16&issue=1&spage=71 DB - PRIME DP - Unbound Medicine ER -