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[Effect of occupational lead exposure on various elements in the human blood. Effects on calcium, cadmium, iron, copper, magnesium, manganese and zinc levels in the human blood, erythrocytes and plasma in vivo].

Abstract

The influence of occupational lead-exposure on calcium, magnesium and trace elements concentration in blood was investigated. We examined 96 lead-exposed persons and for comparison 46 persons without occupational lead exposure. The levels of lead, cadmium, calcium, iron, copper, magnesium, manganese and zinc were determined by atomic absorption spectrometry (AAS) in whole-blood, erythrocytes, as well as in plasma. The median of the lead-concentration in whole blood of the exposed group was 646 micrograms/l (+/- 66.6%-range: 449-814 micrograms/l). For the normal persons a median of 148 micrograms Pb/l (+/- 66.6%-range: 107-235 micrograms Pb/l) was calculated. In whole-blood, erythrocytes and plasma all element-concentrations of the non-exposed persons were in the normal ranges. The lead-exposed workers showed a higher manganese level. The other elements were found in normal values for this group. Increasing lead-concentrations in blood correlated with elevated levels of manganese and zinc in whole-blood, erythrocytes and plasma. The lead workers showed for the whole-blood manganese concentration a median of 14.2 micrograms/l (+/- 66.6%-range: 8.5-22.3 micrograms/l), for zinc a median of 6.3 mg/l (+/- 66.6%-range: 5.2-8.2 mg/l). Those levels were significantly higher than the levels of the non-exposed persons. For this group the median concentration of manganese was 4.8 micrograms/l (+/- 66.6%-range: 2.7-8.6 micrograms/l) and 5.7 mg/l (+/- 66.6%-range: 5.1-6.3 mg/l) for zinc respectively. For zinc positive correlation between blood lead levels and the levels of manganese and zinc in the three blood-compartments was found. An essential change of the element concentrations between erythrocytes and plasma, in the sense of a displacement from one blood-compartment to the other could not be detected.

Pub Type(s)

Comparative Study
English Abstract
Journal Article

Language

ger

PubMed ID

6475377

Citation

Truckenbrodt, R, et al. "[Effect of Occupational Lead Exposure On Various Elements in the Human Blood. Effects On Calcium, Cadmium, Iron, Copper, Magnesium, Manganese and Zinc Levels in the Human Blood, Erythrocytes and Plasma in Vivo]." Zentralblatt Fur Bakteriologie, Mikrobiologie Und Hygiene. 1. Abt. Originale B, Hygiene, vol. 179, no. 3, 1984, pp. 187-97.
Truckenbrodt R, Winter L, Schaller KH. [Effect of occupational lead exposure on various elements in the human blood. Effects on calcium, cadmium, iron, copper, magnesium, manganese and zinc levels in the human blood, erythrocytes and plasma in vivo]. Zentralbl Bakteriol Mikrobiol Hyg B. 1984;179(3):187-97.
Truckenbrodt, R., Winter, L., & Schaller, K. H. (1984). [Effect of occupational lead exposure on various elements in the human blood. Effects on calcium, cadmium, iron, copper, magnesium, manganese and zinc levels in the human blood, erythrocytes and plasma in vivo]. Zentralblatt Fur Bakteriologie, Mikrobiologie Und Hygiene. 1. Abt. Originale B, Hygiene, 179(3), pp. 187-97.
Truckenbrodt R, Winter L, Schaller KH. [Effect of Occupational Lead Exposure On Various Elements in the Human Blood. Effects On Calcium, Cadmium, Iron, Copper, Magnesium, Manganese and Zinc Levels in the Human Blood, Erythrocytes and Plasma in Vivo]. Zentralbl Bakteriol Mikrobiol Hyg B. 1984;179(3):187-97. PubMed PMID: 6475377.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - [Effect of occupational lead exposure on various elements in the human blood. Effects on calcium, cadmium, iron, copper, magnesium, manganese and zinc levels in the human blood, erythrocytes and plasma in vivo]. AU - Truckenbrodt,R, AU - Winter,L, AU - Schaller,K H, PY - 1984/6/1/pubmed PY - 1984/6/1/medline PY - 1984/6/1/entrez SP - 187 EP - 97 JF - Zentralblatt fur Bakteriologie, Mikrobiologie und Hygiene. 1. Abt. Originale B, Hygiene JO - Zentralbl Bakteriol Mikrobiol Hyg B VL - 179 IS - 3 N2 - The influence of occupational lead-exposure on calcium, magnesium and trace elements concentration in blood was investigated. We examined 96 lead-exposed persons and for comparison 46 persons without occupational lead exposure. The levels of lead, cadmium, calcium, iron, copper, magnesium, manganese and zinc were determined by atomic absorption spectrometry (AAS) in whole-blood, erythrocytes, as well as in plasma. The median of the lead-concentration in whole blood of the exposed group was 646 micrograms/l (+/- 66.6%-range: 449-814 micrograms/l). For the normal persons a median of 148 micrograms Pb/l (+/- 66.6%-range: 107-235 micrograms Pb/l) was calculated. In whole-blood, erythrocytes and plasma all element-concentrations of the non-exposed persons were in the normal ranges. The lead-exposed workers showed a higher manganese level. The other elements were found in normal values for this group. Increasing lead-concentrations in blood correlated with elevated levels of manganese and zinc in whole-blood, erythrocytes and plasma. The lead workers showed for the whole-blood manganese concentration a median of 14.2 micrograms/l (+/- 66.6%-range: 8.5-22.3 micrograms/l), for zinc a median of 6.3 mg/l (+/- 66.6%-range: 5.2-8.2 mg/l). Those levels were significantly higher than the levels of the non-exposed persons. For this group the median concentration of manganese was 4.8 micrograms/l (+/- 66.6%-range: 2.7-8.6 micrograms/l) and 5.7 mg/l (+/- 66.6%-range: 5.1-6.3 mg/l) for zinc respectively. For zinc positive correlation between blood lead levels and the levels of manganese and zinc in the three blood-compartments was found. An essential change of the element concentrations between erythrocytes and plasma, in the sense of a displacement from one blood-compartment to the other could not be detected. SN - 0174-3015 UR - https://www.unboundmedicine.com/medline/citation/6475377/[Effect_of_occupational_lead_exposure_on_various_elements_in_the_human_blood__Effects_on_calcium_cadmium_iron_copper_magnesium_manganese_and_zinc_levels_in_the_human_blood_erythrocytes_and_plasma_in_vivo]_ DB - PRIME DP - Unbound Medicine ER -