[Results of sputum cytology in bronchogenic carcinoma--a correlation with patient survival].Gan No Rinsho. 1984 Aug; 30(10):1235-40.GN
In a study of 65 of patients with bronchogenic carcinoma who had thoracotomy over a 5-year period, cytodiagnosis by 3-day consecutive sputum cytology was reported positive for malignant cells in 55.4%. Data analysis revealed that the overall cytodiagnosis correlated with clinical stage, tumor size, site of origin, topography and histologic types. From the histologic standpoint, the site of origin was significantly related to the positive cytology in patients with squamous cell carcinoma among factors influencing the results of sputum cytology. On the other hand, there was a correlation of tumor size and the positive cytology in patients with adenocarcinoma. In addition, poor prognosis related to the positive cytology in adenocarcinoma cases in terms of the relationship between the results through sputum examination and survival. The authors emphasized that sputum cytology has proven to be a valuable factor for determining prognosis, especially in patients with adenocarcinoma.