Tags

Type your tag names separated by a space and hit enter

The Meckel syndrome in Finland: epidemiologic and genetic aspects.
Am J Med Genet. 1984 Aug; 18(4):691-8.AJ

Abstract

Estimates of the incidence of the Meckel syndrome (MS) from different parts of the world vary from 1:140,000 to 1:13,250 births. In this nationwide study performed in Finland, the incidence of 1:14,400 births was found by retrospective ascertainment during the period 1970-1979, while the incidence was 1:8,500 births when prospective monitoring was performed in 1980-1981. The most probable incidence in Finland is about 1:9,000 births. Autosomal recessive inheritance of MS is confirmed in this study. The ratio of affected sibs, corrected for truncate complete ascertainment, was 0.261. No consanguinity between parents was found, as marriages between close relatives are rare in Finland and the ancestors were not traced back far enough to find remote consanguinities.

Authors

Salonen R
No affiliation info available
Norio R
No affiliation info available

MeSH

Abnormalities, MultipleAdultConsanguinityEncephaloceleFemaleFingersFinlandGenes, RecessiveHumansInfant, NewbornMalePolycystic Kidney DiseasesRetrospective StudiesSex RatioSyndromeToes

Pub Type(s)

Journal Article
Research Support, Non-U.S. Gov't

Language

eng

PubMed ID

6486168

Citation

Salonen, R, and R Norio. "The Meckel Syndrome in Finland: Epidemiologic and Genetic Aspects." American Journal of Medical Genetics, vol. 18, no. 4, 1984, pp. 691-8.
Salonen R, Norio R. The Meckel syndrome in Finland: epidemiologic and genetic aspects. Am J Med Genet. 1984;18(4):691-8.
Salonen, R., & Norio, R. (1984). The Meckel syndrome in Finland: epidemiologic and genetic aspects. American Journal of Medical Genetics, 18(4), 691-8.
Salonen R, Norio R. The Meckel Syndrome in Finland: Epidemiologic and Genetic Aspects. Am J Med Genet. 1984;18(4):691-8. PubMed PMID: 6486168.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - The Meckel syndrome in Finland: epidemiologic and genetic aspects. AU - Salonen,R, AU - Norio,R, PY - 1984/8/1/pubmed PY - 1984/8/1/medline PY - 1984/8/1/entrez SP - 691 EP - 8 JF - American journal of medical genetics JO - Am J Med Genet VL - 18 IS - 4 N2 - Estimates of the incidence of the Meckel syndrome (MS) from different parts of the world vary from 1:140,000 to 1:13,250 births. In this nationwide study performed in Finland, the incidence of 1:14,400 births was found by retrospective ascertainment during the period 1970-1979, while the incidence was 1:8,500 births when prospective monitoring was performed in 1980-1981. The most probable incidence in Finland is about 1:9,000 births. Autosomal recessive inheritance of MS is confirmed in this study. The ratio of affected sibs, corrected for truncate complete ascertainment, was 0.261. No consanguinity between parents was found, as marriages between close relatives are rare in Finland and the ancestors were not traced back far enough to find remote consanguinities. SN - 0148-7299 UR - https://www.unboundmedicine.com/medline/citation/6486168/The_Meckel_syndrome_in_Finland:_epidemiologic_and_genetic_aspects_ DB - PRIME DP - Unbound Medicine ER -