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Permeability to sodium ions of the endolymph-perilymph barrier.
Hear Res. 1984 Aug; 15(2):143-9.HR

Abstract

The endocochlear potential and Na+ activity in the endolymph were simultaneously measured with a double-barreled Na+ selective liquid membrane electrode. The modified Na+ conductance and permeability coefficient of the endolymph-perilymph barrier were calculated from the rate of change in the endolymph Na+ concentration relative to the Na+ electrochemical gradient across the barrier during permanent anoxia. In normal guinea pigs the Na+ conductance of the endolymph-perilymph barrier is approximately 5 times less than its K+ conductance. Exposure to noise or treatment with kanamycin suppresses the cochlear microphonics but does not result in significant alterations in the Na+ permeability of the endolymph-perilymph barrier. It is likely that the Na+ permeability of the endolymph-perilymph barrier is not involved in the physiological processes which lead to the cochlear damage produced by noise or kanamycin.

Authors

No affiliation info availableNo affiliation info available

Pub Type(s)

Journal Article

Language

eng

PubMed ID

6490540

Citation

Konishi, T, and H Mori. "Permeability to Sodium Ions of the Endolymph-perilymph Barrier." Hearing Research, vol. 15, no. 2, 1984, pp. 143-9.
Konishi T, Mori H. Permeability to sodium ions of the endolymph-perilymph barrier. Hear Res. 1984;15(2):143-9.
Konishi, T., & Mori, H. (1984). Permeability to sodium ions of the endolymph-perilymph barrier. Hearing Research, 15(2), 143-9.
Konishi T, Mori H. Permeability to Sodium Ions of the Endolymph-perilymph Barrier. Hear Res. 1984;15(2):143-9. PubMed PMID: 6490540.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Permeability to sodium ions of the endolymph-perilymph barrier. AU - Konishi,T, AU - Mori,H, PY - 1984/8/1/pubmed PY - 1984/8/1/medline PY - 1984/8/1/entrez SP - 143 EP - 9 JF - Hearing research JO - Hear. Res. VL - 15 IS - 2 N2 - The endocochlear potential and Na+ activity in the endolymph were simultaneously measured with a double-barreled Na+ selective liquid membrane electrode. The modified Na+ conductance and permeability coefficient of the endolymph-perilymph barrier were calculated from the rate of change in the endolymph Na+ concentration relative to the Na+ electrochemical gradient across the barrier during permanent anoxia. In normal guinea pigs the Na+ conductance of the endolymph-perilymph barrier is approximately 5 times less than its K+ conductance. Exposure to noise or treatment with kanamycin suppresses the cochlear microphonics but does not result in significant alterations in the Na+ permeability of the endolymph-perilymph barrier. It is likely that the Na+ permeability of the endolymph-perilymph barrier is not involved in the physiological processes which lead to the cochlear damage produced by noise or kanamycin. SN - 0378-5955 UR - https://www.unboundmedicine.com/medline/citation/6490540/Permeability_to_sodium_ions_of_the_endolymph_perilymph_barrier_ L2 - https://linkinghub.elsevier.com/retrieve/pii/0378-5955(84)90045-5 DB - PRIME DP - Unbound Medicine ER -