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[Trans-cerebral electrophoresis of L-DOPA in the complex treatment of parkinsonism].
Zh Nevropatol Psikhiatr Im S S Korsakova. 1984; 84(9):1334-8.ZN

Abstract

Based on the established electrophoretic mobility of L-DOPA and on pathogenetic assumptions, the authors carried out multiple modality treatment employing transcerebral L-DOPA electrophoresis in 48 patients with postencephalic and atherosclerotic parkinsonism. The majority of patients (43 subjects) showed an improvement of various degrees, particularly when rigidity and oligo- and bradykinesia were predominant in the clinical picture of the disease. Of the 48 patients treated, 29 received L-DOPA per os and 19 patients were given low drug doses. The therapeutic effect persisted from 2 weeks to 2-3 months.

Authors

Neĭmark EZ
No affiliation info available
Evtushenko SK
No affiliation info available
Dukhovnaia MA
No affiliation info available

MeSH

Administration, OralAdultAgedCombined Modality TherapyElectrophoresisFemaleHumansIntracranial ArteriosclerosisLevodopaMaleMiddle AgedParkinson DiseaseParkinson Disease, PostencephaliticParkinson Disease, Secondary

Pub Type(s)

English Abstract
Journal Article

Language

rus

PubMed ID

6506979

Citation

Neĭmark, E Z., et al. "[Trans-cerebral Electrophoresis of L-DOPA in the Complex Treatment of Parkinsonism]." Zhurnal Nevropatologii I Psikhiatrii Imeni S.S. Korsakova (Moscow, Russia : 1952), vol. 84, no. 9, 1984, pp. 1334-8.
Neĭmark EZ, Evtushenko SK, Dukhovnaia MA. [Trans-cerebral electrophoresis of L-DOPA in the complex treatment of parkinsonism]. Zh Nevropatol Psikhiatr Im S S Korsakova. 1984;84(9):1334-8.
Neĭmark, E. Z., Evtushenko, S. K., & Dukhovnaia, M. A. (1984). [Trans-cerebral electrophoresis of L-DOPA in the complex treatment of parkinsonism]. Zhurnal Nevropatologii I Psikhiatrii Imeni S.S. Korsakova (Moscow, Russia : 1952), 84(9), 1334-8.
Neĭmark EZ, Evtushenko SK, Dukhovnaia MA. [Trans-cerebral Electrophoresis of L-DOPA in the Complex Treatment of Parkinsonism]. Zh Nevropatol Psikhiatr Im S S Korsakova. 1984;84(9):1334-8. PubMed PMID: 6506979.
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TY - JOUR T1 - [Trans-cerebral electrophoresis of L-DOPA in the complex treatment of parkinsonism]. AU - Neĭmark,E Z, AU - Evtushenko,S K, AU - Dukhovnaia,M A, PY - 1984/1/1/pubmed PY - 1984/1/1/medline PY - 1984/1/1/entrez SP - 1334 EP - 8 JF - Zhurnal nevropatologii i psikhiatrii imeni S.S. Korsakova (Moscow, Russia : 1952) JO - Zh Nevropatol Psikhiatr Im S S Korsakova VL - 84 IS - 9 N2 - Based on the established electrophoretic mobility of L-DOPA and on pathogenetic assumptions, the authors carried out multiple modality treatment employing transcerebral L-DOPA electrophoresis in 48 patients with postencephalic and atherosclerotic parkinsonism. The majority of patients (43 subjects) showed an improvement of various degrees, particularly when rigidity and oligo- and bradykinesia were predominant in the clinical picture of the disease. Of the 48 patients treated, 29 received L-DOPA per os and 19 patients were given low drug doses. The therapeutic effect persisted from 2 weeks to 2-3 months. SN - 0044-4588 UR - https://www.unboundmedicine.com/medline/citation/6506979/[Trans_cerebral_electrophoresis_of_L_DOPA_in_the_complex_treatment_of_parkinsonism]_ L2 - https://medlineplus.gov/parkinsonsdisease.html DB - PRIME DP - Unbound Medicine ER -