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[Trans-cerebral electrophoresis of L-DOPA in the complex treatment of parkinsonism].

Abstract

Based on the established electrophoretic mobility of L-DOPA and on pathogenetic assumptions, the authors carried out multiple modality treatment employing transcerebral L-DOPA electrophoresis in 48 patients with postencephalic and atherosclerotic parkinsonism. The majority of patients (43 subjects) showed an improvement of various degrees, particularly when rigidity and oligo- and bradykinesia were predominant in the clinical picture of the disease. Of the 48 patients treated, 29 received L-DOPA per os and 19 patients were given low drug doses. The therapeutic effect persisted from 2 weeks to 2-3 months.

Authors

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Pub Type(s)

English Abstract
Journal Article

Language

rus

PubMed ID

6506979

Citation

Neĭmark, E Z., et al. "[Trans-cerebral Electrophoresis of L-DOPA in the Complex Treatment of Parkinsonism]." Zhurnal Nevropatologii I Psikhiatrii Imeni S.S. Korsakova (Moscow, Russia : 1952), vol. 84, no. 9, 1984, pp. 1334-8.
Neĭmark EZ, Evtushenko SK, Dukhovnaia MA. [Trans-cerebral electrophoresis of L-DOPA in the complex treatment of parkinsonism]. Zh Nevropatol Psikhiatr Im S S Korsakova. 1984;84(9):1334-8.
Neĭmark, E. Z., Evtushenko, S. K., & Dukhovnaia, M. A. (1984). [Trans-cerebral electrophoresis of L-DOPA in the complex treatment of parkinsonism]. Zhurnal Nevropatologii I Psikhiatrii Imeni S.S. Korsakova (Moscow, Russia : 1952), 84(9), 1334-8.
Neĭmark EZ, Evtushenko SK, Dukhovnaia MA. [Trans-cerebral Electrophoresis of L-DOPA in the Complex Treatment of Parkinsonism]. Zh Nevropatol Psikhiatr Im S S Korsakova. 1984;84(9):1334-8. PubMed PMID: 6506979.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - [Trans-cerebral electrophoresis of L-DOPA in the complex treatment of parkinsonism]. AU - Neĭmark,E Z, AU - Evtushenko,S K, AU - Dukhovnaia,M A, PY - 1984/1/1/pubmed PY - 1984/1/1/medline PY - 1984/1/1/entrez SP - 1334 EP - 8 JF - Zhurnal nevropatologii i psikhiatrii imeni S.S. Korsakova (Moscow, Russia : 1952) JO - Zh Nevropatol Psikhiatr Im S S Korsakova VL - 84 IS - 9 N2 - Based on the established electrophoretic mobility of L-DOPA and on pathogenetic assumptions, the authors carried out multiple modality treatment employing transcerebral L-DOPA electrophoresis in 48 patients with postencephalic and atherosclerotic parkinsonism. The majority of patients (43 subjects) showed an improvement of various degrees, particularly when rigidity and oligo- and bradykinesia were predominant in the clinical picture of the disease. Of the 48 patients treated, 29 received L-DOPA per os and 19 patients were given low drug doses. The therapeutic effect persisted from 2 weeks to 2-3 months. SN - 0044-4588 UR - https://www.unboundmedicine.com/medline/citation/6506979/[Trans_cerebral_electrophoresis_of_L_DOPA_in_the_complex_treatment_of_parkinsonism]_ L2 - https://medlineplus.gov/parkinsonsdisease.html DB - PRIME DP - Unbound Medicine ER -