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Primary gastrin cell hyperplasia. Report of five cases and a review of the literature.
Am J Surg Pathol. 1984 Nov; 8(11):821-32.AJ

Abstract

Primary gastrin cell hyperfunction of the gastric antrum as a clinical syndrome consists of basal hypergastrinemia, an exaggerated gastrin response to feeding, the absence of any ectopic source of gastrin secretion, and peptic ulcer disease. The number of G-cells were quantitated in the gastric antrum of five patients with clinically diagnosed primary G-cell hyperfunction, and the results were compared to controls with a variety of gastric diseases. Patients with the clinical diagnosis of primary G-cell hyperfunction had a significantly increased number of antral G-cells (p less than 0.05). The clinical syndrome of primary G-cell hyperplasia appears to be associated with hyperplasia of G-cells rather than with the hypersecretion of gastrin by a normal number of G-cells.

Authors

No affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info available

Pub Type(s)

Case Reports
Journal Article
Research Support, U.S. Gov't, P.H.S.

Language

eng

PubMed ID

6507721

Citation

Lewin, K J., et al. "Primary Gastrin Cell Hyperplasia. Report of Five Cases and a Review of the Literature." The American Journal of Surgical Pathology, vol. 8, no. 11, 1984, pp. 821-32.
Lewin KJ, Yang K, Ulich T, et al. Primary gastrin cell hyperplasia. Report of five cases and a review of the literature. Am J Surg Pathol. 1984;8(11):821-32.
Lewin, K. J., Yang, K., Ulich, T., Elashoff, J. D., & Walsh, J. (1984). Primary gastrin cell hyperplasia. Report of five cases and a review of the literature. The American Journal of Surgical Pathology, 8(11), 821-32.
Lewin KJ, et al. Primary Gastrin Cell Hyperplasia. Report of Five Cases and a Review of the Literature. Am J Surg Pathol. 1984;8(11):821-32. PubMed PMID: 6507721.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Primary gastrin cell hyperplasia. Report of five cases and a review of the literature. AU - Lewin,K J, AU - Yang,K, AU - Ulich,T, AU - Elashoff,J D, AU - Walsh,J, PY - 1984/11/1/pubmed PY - 1984/11/1/medline PY - 1984/11/1/entrez SP - 821 EP - 32 JF - The American journal of surgical pathology JO - Am J Surg Pathol VL - 8 IS - 11 N2 - Primary gastrin cell hyperfunction of the gastric antrum as a clinical syndrome consists of basal hypergastrinemia, an exaggerated gastrin response to feeding, the absence of any ectopic source of gastrin secretion, and peptic ulcer disease. The number of G-cells were quantitated in the gastric antrum of five patients with clinically diagnosed primary G-cell hyperfunction, and the results were compared to controls with a variety of gastric diseases. Patients with the clinical diagnosis of primary G-cell hyperfunction had a significantly increased number of antral G-cells (p less than 0.05). The clinical syndrome of primary G-cell hyperplasia appears to be associated with hyperplasia of G-cells rather than with the hypersecretion of gastrin by a normal number of G-cells. SN - 0147-5185 UR - https://www.unboundmedicine.com/medline/citation/6507721/Primary_gastrin_cell_hyperplasia__Report_of_five_cases_and_a_review_of_the_literature_ L2 - http://ovidsp.ovid.com/ovidweb.cgi?T=JS&PAGE=linkout&SEARCH=6507721.ui DB - PRIME DP - Unbound Medicine ER -