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15-Deacetylsergeolide, a potent antileukemic quassinoid from Picrolemma pseudocoffea.
J Nat Prod. 1984 Nov-Dec; 47(6):994-6.JN

Abstract

Investigation of the leaf extract of Picrolemma pseudocoffea afforded a new antineoplastic quassinoid, 15-deacetylsergeolide (3), and two known quassinoids, isobruceine B (1) and sergeolide (2). The structure of 3, which displayed strong antileukemic activity in the P-388 test system, was established through the interpretation of spectral data and chemical correlation to 2.

Authors

No affiliation info availableNo affiliation info availableNo affiliation info available

Pub Type(s)

Journal Article
Research Support, U.S. Gov't, P.H.S.

Language

eng

PubMed ID

6533270

Citation

Polonsky, J, et al. "15-Deacetylsergeolide, a Potent Antileukemic Quassinoid From Picrolemma Pseudocoffea." Journal of Natural Products, vol. 47, no. 6, 1984, pp. 994-6.
Polonsky J, Bhatnagar S, Moretti C. 15-Deacetylsergeolide, a potent antileukemic quassinoid from Picrolemma pseudocoffea. J Nat Prod. 1984;47(6):994-6.
Polonsky, J., Bhatnagar, S., & Moretti, C. (1984). 15-Deacetylsergeolide, a potent antileukemic quassinoid from Picrolemma pseudocoffea. Journal of Natural Products, 47(6), 994-6.
Polonsky J, Bhatnagar S, Moretti C. 15-Deacetylsergeolide, a Potent Antileukemic Quassinoid From Picrolemma Pseudocoffea. J Nat Prod. 1984 Nov-Dec;47(6):994-6. PubMed PMID: 6533270.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - 15-Deacetylsergeolide, a potent antileukemic quassinoid from Picrolemma pseudocoffea. AU - Polonsky,J, AU - Bhatnagar,S, AU - Moretti,C, PY - 1984/11/1/pubmed PY - 1984/11/1/medline PY - 1984/11/1/entrez SP - 994 EP - 6 JF - Journal of natural products JO - J Nat Prod VL - 47 IS - 6 N2 - Investigation of the leaf extract of Picrolemma pseudocoffea afforded a new antineoplastic quassinoid, 15-deacetylsergeolide (3), and two known quassinoids, isobruceine B (1) and sergeolide (2). The structure of 3, which displayed strong antileukemic activity in the P-388 test system, was established through the interpretation of spectral data and chemical correlation to 2. SN - 0163-3864 UR - https://www.unboundmedicine.com/medline/citation/6533270/15_Deacetylsergeolide_a_potent_antileukemic_quassinoid_from_Picrolemma_pseudocoffea_ DB - PRIME DP - Unbound Medicine ER -