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A case of Behçet's disease associated with membranous nephropathy.
Tokai J Exp Clin Med. 1984 Aug; 9(3):231-5.TJ

Abstract

A 35-year-old female patient with Behçet's disease associated with nephrotic syndrome is described. Renal biopsy specimens revealed typical features of membranous nephropathy in light microscopical, electron microscopical and immunofluorescent microscopical examinations. Circulating immune complexes (IC) phagocytized by polymorphonuclear leukocytes (PMN) in this patient were significantly increased compared with those in healthy adults. Recurrent oral aphthous ulcers had persisted for 14 years. In the course of Behçet's disease, nephrotic syndrome due to membranous nephropathy was observed. Depositions of IgA, IgM, C3 and C4 were observed in the subcutaneous arteriolar walls by immunofluorescence. It is suggested that the pathogenesis of Behçet's disease and membranous nephropathy might be due to a deposition of circulating immune complexes in various types of vascular vessels in this patient.

Authors

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Pub Type(s)

Case Reports
Journal Article

Language

eng

PubMed ID

6537671

Citation

Miura, M, et al. "A Case of Behçet's Disease Associated With Membranous Nephropathy." The Tokai Journal of Experimental and Clinical Medicine, vol. 9, no. 3, 1984, pp. 231-5.
Miura M, Tomino Y, Suga T, et al. A case of Behçet's disease associated with membranous nephropathy. Tokai J Exp Clin Med. 1984;9(3):231-5.
Miura, M., Tomino, Y., Suga, T., Endoh, M., Nomoto, Y., Sakai, H., Furuya, K., & Kobayashi, Y. (1984). A case of Behçet's disease associated with membranous nephropathy. The Tokai Journal of Experimental and Clinical Medicine, 9(3), 231-5.
Miura M, et al. A Case of Behçet's Disease Associated With Membranous Nephropathy. Tokai J Exp Clin Med. 1984;9(3):231-5. PubMed PMID: 6537671.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - A case of Behçet's disease associated with membranous nephropathy. AU - Miura,M, AU - Tomino,Y, AU - Suga,T, AU - Endoh,M, AU - Nomoto,Y, AU - Sakai,H, AU - Furuya,K, AU - Kobayashi,Y, PY - 1984/8/1/pubmed PY - 1984/8/1/medline PY - 1984/8/1/entrez SP - 231 EP - 5 JF - The Tokai journal of experimental and clinical medicine JO - Tokai J. Exp. Clin. Med. VL - 9 IS - 3 N2 - A 35-year-old female patient with Behçet's disease associated with nephrotic syndrome is described. Renal biopsy specimens revealed typical features of membranous nephropathy in light microscopical, electron microscopical and immunofluorescent microscopical examinations. Circulating immune complexes (IC) phagocytized by polymorphonuclear leukocytes (PMN) in this patient were significantly increased compared with those in healthy adults. Recurrent oral aphthous ulcers had persisted for 14 years. In the course of Behçet's disease, nephrotic syndrome due to membranous nephropathy was observed. Depositions of IgA, IgM, C3 and C4 were observed in the subcutaneous arteriolar walls by immunofluorescence. It is suggested that the pathogenesis of Behçet's disease and membranous nephropathy might be due to a deposition of circulating immune complexes in various types of vascular vessels in this patient. SN - 0385-0005 UR - https://www.unboundmedicine.com/medline/citation/6537671/A_case_of_Behçet's_disease_associated_with_membranous_nephropathy_ L2 - http://www.diseaseinfosearch.org/result/4590 DB - PRIME DP - Unbound Medicine ER -