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Behavioral effects of piracetam in rats with isolation syndrome.
Acta Physiol Pharmacol Bulg. 1984; 10(3):3-9.AP

Abstract

Piracetam in doses of 300 and 600 mg/kg i.p. administered for 5 days in Wistar rats with isolation syndrome produced a transient inhibition of mouse-killing behavior. Its anti-aggressive effect was most pronounced on days 2 and 3 of drug administration. On day 5 all aggressive rats again exhibited mouse-killing behavior. Piracetam in both doses was less effective in avoidance learning of aggressive rats. These results suggest that piracetam has a slight effect on the aggressive behavior of rats with isolation syndrome. No relationship exists between the antiaggressive and the learning-facilitating effects of piracetam.

Authors

Petkov VV
No affiliation info available
Rousseva S
No affiliation info available
Dimov S
No affiliation info available

MeSH

AggressionAnimalsAvoidance LearningBrain ChemistryHumansMalePiracetamPyrrolidinonesRatsRats, Inbred StrainsSocial Isolationgamma-Aminobutyric Acid

Pub Type(s)

Journal Article

Language

eng

PubMed ID

6543288

Citation

Petkov, V V., et al. "Behavioral Effects of Piracetam in Rats With Isolation Syndrome." Acta Physiologica Et Pharmacologica Bulgarica, vol. 10, no. 3, 1984, pp. 3-9.
Petkov VV, Rousseva S, Dimov S. Behavioral effects of piracetam in rats with isolation syndrome. Acta Physiol Pharmacol Bulg. 1984;10(3):3-9.
Petkov, V. V., Rousseva, S., & Dimov, S. (1984). Behavioral effects of piracetam in rats with isolation syndrome. Acta Physiologica Et Pharmacologica Bulgarica, 10(3), 3-9.
Petkov VV, Rousseva S, Dimov S. Behavioral Effects of Piracetam in Rats With Isolation Syndrome. Acta Physiol Pharmacol Bulg. 1984;10(3):3-9. PubMed PMID: 6543288.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Behavioral effects of piracetam in rats with isolation syndrome. AU - Petkov,V V, AU - Rousseva,S, AU - Dimov,S, PY - 1984/1/1/pubmed PY - 1984/1/1/medline PY - 1984/1/1/entrez SP - 3 EP - 9 JF - Acta physiologica et pharmacologica Bulgarica JO - Acta Physiol Pharmacol Bulg VL - 10 IS - 3 N2 - Piracetam in doses of 300 and 600 mg/kg i.p. administered for 5 days in Wistar rats with isolation syndrome produced a transient inhibition of mouse-killing behavior. Its anti-aggressive effect was most pronounced on days 2 and 3 of drug administration. On day 5 all aggressive rats again exhibited mouse-killing behavior. Piracetam in both doses was less effective in avoidance learning of aggressive rats. These results suggest that piracetam has a slight effect on the aggressive behavior of rats with isolation syndrome. No relationship exists between the antiaggressive and the learning-facilitating effects of piracetam. SN - 0323-9950 UR - https://www.unboundmedicine.com/medline/citation/6543288/Behavioral_effects_of_piracetam_in_rats_with_isolation_syndrome_ DB - PRIME DP - Unbound Medicine ER -