[Computer calculations on the effect of urine components on saturation relations of calcium oxalate in the urine].Urologe A 1984; 23(2):70-6U
With the help of a computer program the influence of magnesium, citrate, sodium, potassium, chloride and sulfate on the activity product of calcium oxalate is examined in a synthetic and in physiological urine by varying the several parameters. Natural urine shows a significant decrease of the supersaturation of calcium oxalate by enhancing concentration of citrate. A physiological average magnesium concentration shows no effect in the sense of an increase of supersaturation antagonizing the citrate. An additional increase of the concentration of magnesium is barely effective. Citrate shows a greater effect on the decrease of supersaturation of calcium oxalate than comparable quantities of magnesium concentrations. Within the normal range of sodium chloride concentration only a slight change of the supersaturation of calcium oxalate can be observed. Sulfate has also a very slight influence in natural urine within the normal physiological range, whereas potassium does not show any effect at all.