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Gastric mucus secretion in chronic gastritis.
Scand J Gastroenterol Suppl. 1984; 92:167-71.SJ

Abstract

We have studied gastric soluble mucus behaviour in 58 patients with histological evidence of chronic gastritis and without circumscribed lesions of the upper gastrointestinal tract endoscopically demonstrated, compared with a control group of 8 normal subjects. As mucus secretion parameters, the protein component of mucosubstances, glucosamine, fucose, the free NANA and sulphate groups content were determined with biochemical methods. In cases of superficial gastritis, either diffuse or limited to fundus or to antrum with normal remaining mucosa, we have observed a significant decrease of fucomucines and a significant increase of sulphomucines compared with a control group, without significant quantitative variations of total soluble mucus. In cases of diffuse and limited atrophic gastritis there were more significant qualitative variations of soluble mucus characterized by a higher decrease of neutral mucosubstances with a high increase of the acid ones than in cases of superficial gastritis. Quantitative variations of total soluble mucus were present only in the situation of diffuse to fundus and antrum atrophic gastritis.

Authors

Molinari F
No affiliation info available
Parodi MC
No affiliation info available
De Angelis P
No affiliation info available
Cheli R
No affiliation info available

MeSH

AdultFemaleFucoseGastric JuiceGastric MucosaGastritisGastritis, AtrophicGlucosamineHumansMaleMiddle AgedMucusN-Acetylneuraminic AcidSialic AcidsSulfates

Pub Type(s)

Journal Article

Language

eng

PubMed ID

6588508

Citation

Molinari, F, et al. "Gastric Mucus Secretion in Chronic Gastritis." Scandinavian Journal of Gastroenterology. Supplement, vol. 92, 1984, pp. 167-71.
Molinari F, Parodi MC, De Angelis P, et al. Gastric mucus secretion in chronic gastritis. Scand J Gastroenterol Suppl. 1984;92:167-71.
Molinari, F., Parodi, M. C., De Angelis, P., & Cheli, R. (1984). Gastric mucus secretion in chronic gastritis. Scandinavian Journal of Gastroenterology. Supplement, 92, 167-71.
Molinari F, et al. Gastric Mucus Secretion in Chronic Gastritis. Scand J Gastroenterol Suppl. 1984;92:167-71. PubMed PMID: 6588508.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Gastric mucus secretion in chronic gastritis. AU - Molinari,F, AU - Parodi,M C, AU - De Angelis,P, AU - Cheli,R, PY - 1984/1/1/pubmed PY - 1984/1/1/medline PY - 1984/1/1/entrez SP - 167 EP - 71 JF - Scandinavian journal of gastroenterology. Supplement JO - Scand J Gastroenterol Suppl VL - 92 N2 - We have studied gastric soluble mucus behaviour in 58 patients with histological evidence of chronic gastritis and without circumscribed lesions of the upper gastrointestinal tract endoscopically demonstrated, compared with a control group of 8 normal subjects. As mucus secretion parameters, the protein component of mucosubstances, glucosamine, fucose, the free NANA and sulphate groups content were determined with biochemical methods. In cases of superficial gastritis, either diffuse or limited to fundus or to antrum with normal remaining mucosa, we have observed a significant decrease of fucomucines and a significant increase of sulphomucines compared with a control group, without significant quantitative variations of total soluble mucus. In cases of diffuse and limited atrophic gastritis there were more significant qualitative variations of soluble mucus characterized by a higher decrease of neutral mucosubstances with a high increase of the acid ones than in cases of superficial gastritis. Quantitative variations of total soluble mucus were present only in the situation of diffuse to fundus and antrum atrophic gastritis. SN - 0085-5928 UR - https://www.unboundmedicine.com/medline/citation/6588508/Gastric_mucus_secretion_in_chronic_gastritis_ DB - PRIME DP - Unbound Medicine ER -