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The diagnosis of Pneumocystis carinii pneumonia in patients with the acquired immunodeficiency syndrome using subsegmental bronchoalveolar lavage.
Am Rev Respir Dis. 1984 Jun; 129(6):929-32.AR

Abstract

To assess the sensitivity of bronchoalveolar lavage in patients with the acquired immunodeficiency syndrome (AIDS) in diagnosing Pneumocystis carinii pneumonia (PCP), we prospectively performed 27 bronchoalveolar lavages (BAL) in 16 patients either because there was an initially high index of suspicion of PCP or in order to assess therapeutic response to anti-Pneumocystis medication in those patients who had had PCP documented. Pneumocystis organisms were demonstrated on BAL specimens in 16 of 18 procedures in patients with histologic evidence of PCP on simultaneously obtained pulmonary tissue. The diagnosis was established rapidly by BAL and there was no substantial morbidity attributable to the procedure. Subsegmental BAL may be an important and sensitive tool for early diagnosis of PCP in patients with AIDS.

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Authors

Ognibene FP
No affiliation info available
Shelhamer J
No affiliation info available
Gill V
No affiliation info available
Macher AM
No affiliation info available
Loew D
No affiliation info available
Parker MM
No affiliation info available
Gelmann E
No affiliation info available
Fauci AS
No affiliation info available
Parrillo JE
No affiliation info available
Masur H
No affiliation info available

MeSH

Acquired Immunodeficiency SyndromeAdultBiopsyBronchiBronchoscopyHumansMaleMiddle AgedPneumocystisPneumonia, PneumocystisPulmonary AlveoliTherapeutic Irrigation

Pub Type(s)

Comparative Study
Journal Article

Language

eng

PubMed ID

6610373

Citation

Ognibene, F P., et al. "The Diagnosis of Pneumocystis Carinii Pneumonia in Patients With the Acquired Immunodeficiency Syndrome Using Subsegmental Bronchoalveolar Lavage." The American Review of Respiratory Disease, vol. 129, no. 6, 1984, pp. 929-32.
Ognibene FP, Shelhamer J, Gill V, et al. The diagnosis of Pneumocystis carinii pneumonia in patients with the acquired immunodeficiency syndrome using subsegmental bronchoalveolar lavage. Am Rev Respir Dis. 1984;129(6):929-32.
Ognibene, F. P., Shelhamer, J., Gill, V., Macher, A. M., Loew, D., Parker, M. M., Gelmann, E., Fauci, A. S., Parrillo, J. E., & Masur, H. (1984). The diagnosis of Pneumocystis carinii pneumonia in patients with the acquired immunodeficiency syndrome using subsegmental bronchoalveolar lavage. The American Review of Respiratory Disease, 129(6), 929-32.
Ognibene FP, et al. The Diagnosis of Pneumocystis Carinii Pneumonia in Patients With the Acquired Immunodeficiency Syndrome Using Subsegmental Bronchoalveolar Lavage. Am Rev Respir Dis. 1984;129(6):929-32. PubMed PMID: 6610373.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - The diagnosis of Pneumocystis carinii pneumonia in patients with the acquired immunodeficiency syndrome using subsegmental bronchoalveolar lavage. AU - Ognibene,F P, AU - Shelhamer,J, AU - Gill,V, AU - Macher,A M, AU - Loew,D, AU - Parker,M M, AU - Gelmann,E, AU - Fauci,A S, AU - Parrillo,J E, AU - Masur,H, PY - 1984/6/1/pubmed PY - 1984/6/1/medline PY - 1984/6/1/entrez SP - 929 EP - 32 JF - The American review of respiratory disease JO - Am Rev Respir Dis VL - 129 IS - 6 N2 - To assess the sensitivity of bronchoalveolar lavage in patients with the acquired immunodeficiency syndrome (AIDS) in diagnosing Pneumocystis carinii pneumonia (PCP), we prospectively performed 27 bronchoalveolar lavages (BAL) in 16 patients either because there was an initially high index of suspicion of PCP or in order to assess therapeutic response to anti-Pneumocystis medication in those patients who had had PCP documented. Pneumocystis organisms were demonstrated on BAL specimens in 16 of 18 procedures in patients with histologic evidence of PCP on simultaneously obtained pulmonary tissue. The diagnosis was established rapidly by BAL and there was no substantial morbidity attributable to the procedure. Subsegmental BAL may be an important and sensitive tool for early diagnosis of PCP in patients with AIDS. SN - 0003-0805 UR - https://www.unboundmedicine.com/medline/citation/6610373/The_diagnosis_of_Pneumocystis_carinii_pneumonia_in_patients_with_the_acquired_immunodeficiency_syndrome_using_subsegmental_bronchoalveolar_lavage_ L2 - https://www.atsjournals.org/doi/10.1164/arrd.1984.129.6.929?url_ver=Z39.88-2003&rfr_id=ori:rid:crossref.org&rfr_dat=cr_pub=pubmed DB - PRIME DP - Unbound Medicine ER -