Tags

Type your tag names separated by a space and hit enter

[Efficacy of tinidazole against anaerobes in comparison with metronidazole, ornidazole, cefoxitin and lamoxactam].
Immun Infekt. 1983 Jun; 11(4):143-7.II

Abstract

The in vitro inhibitory activity of tinidazole, metronidazole, ornidazole, cefoxitin and moxalactam was determined against 150 isolates of clinically important anaerobes including Bacteroides fragilis, Bacteroides bivius and Clostridium perfringens by means of agar dilution tests. The members of 18 gramnegative and 14 grampositive species were inhibited by tinidazole at less than or equal to 0,01-8 micrograms/ml thus being without exception susceptible to the drug. A similar in vitro activity was recorded for metronidazole and ornidazole. Though cefoxitin and moxalactam generally had a good in vitro activity against most anaerobic species, single strains of Bacteroides thetaiotaomicron, B. distasonis, Clostridium difficile and Eubacterium rectale were resistant to these drugs. With regard to its in vitro activity, tinidazole seems to be a promising substance for the therapy of anaerobic infections.

Authors

No affiliation info availableNo affiliation info availableNo affiliation info available

Pub Type(s)

Comparative Study
English Abstract
Journal Article

Language

ger

PubMed ID

6681175

Citation

Werner, H, et al. "[Efficacy of Tinidazole Against Anaerobes in Comparison With Metronidazole, Ornidazole, Cefoxitin and Lamoxactam]." Immunitat Und Infektion, vol. 11, no. 4, 1983, pp. 143-7.
Werner H, Kuchenbecker K, Hammann R. [Efficacy of tinidazole against anaerobes in comparison with metronidazole, ornidazole, cefoxitin and lamoxactam]. Immun Infekt. 1983;11(4):143-7.
Werner, H., Kuchenbecker, K., & Hammann, R. (1983). [Efficacy of tinidazole against anaerobes in comparison with metronidazole, ornidazole, cefoxitin and lamoxactam]. Immunitat Und Infektion, 11(4), 143-7.
Werner H, Kuchenbecker K, Hammann R. [Efficacy of Tinidazole Against Anaerobes in Comparison With Metronidazole, Ornidazole, Cefoxitin and Lamoxactam]. Immun Infekt. 1983;11(4):143-7. PubMed PMID: 6681175.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - [Efficacy of tinidazole against anaerobes in comparison with metronidazole, ornidazole, cefoxitin and lamoxactam]. AU - Werner,H, AU - Kuchenbecker,K, AU - Hammann,R, PY - 1983/6/1/pubmed PY - 1983/6/1/medline PY - 1983/6/1/entrez SP - 143 EP - 7 JF - Immunitat und Infektion JO - Immun Infekt VL - 11 IS - 4 N2 - The in vitro inhibitory activity of tinidazole, metronidazole, ornidazole, cefoxitin and moxalactam was determined against 150 isolates of clinically important anaerobes including Bacteroides fragilis, Bacteroides bivius and Clostridium perfringens by means of agar dilution tests. The members of 18 gramnegative and 14 grampositive species were inhibited by tinidazole at less than or equal to 0,01-8 micrograms/ml thus being without exception susceptible to the drug. A similar in vitro activity was recorded for metronidazole and ornidazole. Though cefoxitin and moxalactam generally had a good in vitro activity against most anaerobic species, single strains of Bacteroides thetaiotaomicron, B. distasonis, Clostridium difficile and Eubacterium rectale were resistant to these drugs. With regard to its in vitro activity, tinidazole seems to be a promising substance for the therapy of anaerobic infections. UR - https://www.unboundmedicine.com/medline/citation/6681175/[Efficacy_of_tinidazole_against_anaerobes_in_comparison_with_metronidazole_ornidazole_cefoxitin_and_lamoxactam]_ DB - PRIME DP - Unbound Medicine ER -