Tags

Type your tag names separated by a space and hit enter

Colorectal cancer in rural Nebraska.
Cancer Res. 1984 Jan; 44(1):363-9.CR

Abstract

A case-control interview study of colorectal cancer was conducted in two rural counties of eastern Nebraska to determine reasons for the elevated colon cancer mortality rates during 1950 to 1969. Comparison of the information provided by 86 colorectal cancer cases and 176 matched controls (or their next of kin) revealed an increased risk among persons of Czech background, with persons of Bohemian and Moravian extraction predominating in this area. The data suggest an interaction between Bohemian ancestry and certain dietary patterns in the pathogenesis of colon cancer in this region. Colon cancer risk was elevated among commercial beer drinkers regardless of their ethnic background, although Bohemians reported heavier consumption. An excess risk was also associated with intestinal polyps, reported more often by Moravians, and with familial occurrence of gastrointestinal and other cancers. Since 1969, the mortality and incidence rates for colon cancer in this area have declined, possibly as a consequence of acculturation of the American-born descendants of Czech immigrants.

Authors

Pickle LW
No affiliation info available
Greene MH
No affiliation info available
Ziegler RG
No affiliation info available
Toledo A
No affiliation info available
Hoover R
No affiliation info available
Lynch HT
No affiliation info available
Fraumeni JF
No affiliation info available

MeSH

Age FactorsAgedAlcohol DrinkingColonic NeoplasmsCzechoslovakiaDietEthnicityFemaleHumansMaleMiddle AgedNebraskaRectal NeoplasmsRural PopulationSex FactorsSmoking

Pub Type(s)

Journal Article
Research Support, U.S. Gov't, P.H.S.

Language

eng

PubMed ID

6690049

Citation

Pickle, L W., et al. "Colorectal Cancer in Rural Nebraska." Cancer Research, vol. 44, no. 1, 1984, pp. 363-9.
Pickle LW, Greene MH, Ziegler RG, et al. Colorectal cancer in rural Nebraska. Cancer Res. 1984;44(1):363-9.
Pickle, L. W., Greene, M. H., Ziegler, R. G., Toledo, A., Hoover, R., Lynch, H. T., & Fraumeni, J. F. (1984). Colorectal cancer in rural Nebraska. Cancer Research, 44(1), 363-9.
Pickle LW, et al. Colorectal Cancer in Rural Nebraska. Cancer Res. 1984;44(1):363-9. PubMed PMID: 6690049.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Colorectal cancer in rural Nebraska. AU - Pickle,L W, AU - Greene,M H, AU - Ziegler,R G, AU - Toledo,A, AU - Hoover,R, AU - Lynch,H T, AU - Fraumeni,J F,Jr PY - 1984/1/1/pubmed PY - 2001/3/28/medline PY - 1984/1/1/entrez SP - 363 EP - 9 JF - Cancer research JO - Cancer Res VL - 44 IS - 1 N2 - A case-control interview study of colorectal cancer was conducted in two rural counties of eastern Nebraska to determine reasons for the elevated colon cancer mortality rates during 1950 to 1969. Comparison of the information provided by 86 colorectal cancer cases and 176 matched controls (or their next of kin) revealed an increased risk among persons of Czech background, with persons of Bohemian and Moravian extraction predominating in this area. The data suggest an interaction between Bohemian ancestry and certain dietary patterns in the pathogenesis of colon cancer in this region. Colon cancer risk was elevated among commercial beer drinkers regardless of their ethnic background, although Bohemians reported heavier consumption. An excess risk was also associated with intestinal polyps, reported more often by Moravians, and with familial occurrence of gastrointestinal and other cancers. Since 1969, the mortality and incidence rates for colon cancer in this area have declined, possibly as a consequence of acculturation of the American-born descendants of Czech immigrants. SN - 0008-5472 UR - https://www.unboundmedicine.com/medline/citation/6690049/Colorectal_cancer_in_rural_Nebraska_ DB - PRIME DP - Unbound Medicine ER -