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Anorectal sensorimotor dysfunction in fecal incontinence and diabetes mellitus. Modification with biofeedback therapy.
N Engl J Med. 1984 May 17; 310(20):1282-7.NEJM

Abstract

We studied anorectal sensory and motor function in 14 diabetics with fecal incontinence and compared the results with those in 13 continent diabetics, 31 nondiabetics with fecal incontinence, and 11 continent nondiabetics. The threshold volume at which diabetic patients with fecal incontinence experienced rectal sensation was higher (25.0 +/- 3.4 ml [mean +/- S.E.M.]) than that in continent diabetics (13.0 +/- 2.4 ml) or nondiabetics with or without incontinence (14.5 +/- 1.5 and 12.5 +/- 1.8 ml, respectively; P less than 0.02). Biofeedback conditioning in 11 incontinent diabetics led to normal sensory thresholds in six of seven patients with pretreatment thresholds above 20 ml; five of these six became continent. Biofeedback also improved external-sphincter function in nine diabetics, eight of whom became continent. Overall, 8 of 11 diabetics had a reduction in fecal soiling after biofeedback therapy. We conclude that fecal incontinence in diabetics may be caused by decreased rectal sensation or impaired function of the external sphincter or both, and that these abnormalities can often be improved by biofeedback therapy with resultant reestablishment of bowel control.

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Publisher Full Text

Authors

Wald A
No affiliation info available
Tunuguntla AK
No affiliation info available

MeSH

AdultAnal CanalBiofeedback, PsychologyDefecationDiabetes ComplicationsDiabetes MellitusFecal IncontinenceFemaleHumansMaleManometryMiddle AgedMotor ActivityRectumSensationSensory Thresholds

Pub Type(s)

Journal Article

Language

eng

PubMed ID

6717494

Citation

Wald, A, and A K. Tunuguntla. "Anorectal Sensorimotor Dysfunction in Fecal Incontinence and Diabetes Mellitus. Modification With Biofeedback Therapy." The New England Journal of Medicine, vol. 310, no. 20, 1984, pp. 1282-7.
Wald A, Tunuguntla AK. Anorectal sensorimotor dysfunction in fecal incontinence and diabetes mellitus. Modification with biofeedback therapy. N Engl J Med. 1984;310(20):1282-7.
Wald, A., & Tunuguntla, A. K. (1984). Anorectal sensorimotor dysfunction in fecal incontinence and diabetes mellitus. Modification with biofeedback therapy. The New England Journal of Medicine, 310(20), 1282-7.
Wald A, Tunuguntla AK. Anorectal Sensorimotor Dysfunction in Fecal Incontinence and Diabetes Mellitus. Modification With Biofeedback Therapy. N Engl J Med. 1984 May 17;310(20):1282-7. PubMed PMID: 6717494.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Anorectal sensorimotor dysfunction in fecal incontinence and diabetes mellitus. Modification with biofeedback therapy. AU - Wald,A, AU - Tunuguntla,A K, PY - 1984/5/17/pubmed PY - 1984/5/17/medline PY - 1984/5/17/entrez SP - 1282 EP - 7 JF - The New England journal of medicine JO - N Engl J Med VL - 310 IS - 20 N2 - We studied anorectal sensory and motor function in 14 diabetics with fecal incontinence and compared the results with those in 13 continent diabetics, 31 nondiabetics with fecal incontinence, and 11 continent nondiabetics. The threshold volume at which diabetic patients with fecal incontinence experienced rectal sensation was higher (25.0 +/- 3.4 ml [mean +/- S.E.M.]) than that in continent diabetics (13.0 +/- 2.4 ml) or nondiabetics with or without incontinence (14.5 +/- 1.5 and 12.5 +/- 1.8 ml, respectively; P less than 0.02). Biofeedback conditioning in 11 incontinent diabetics led to normal sensory thresholds in six of seven patients with pretreatment thresholds above 20 ml; five of these six became continent. Biofeedback also improved external-sphincter function in nine diabetics, eight of whom became continent. Overall, 8 of 11 diabetics had a reduction in fecal soiling after biofeedback therapy. We conclude that fecal incontinence in diabetics may be caused by decreased rectal sensation or impaired function of the external sphincter or both, and that these abnormalities can often be improved by biofeedback therapy with resultant reestablishment of bowel control. SN - 0028-4793 UR - https://www.unboundmedicine.com/medline/citation/6717494/Anorectal_sensorimotor_dysfunction_in_fecal_incontinence_and_diabetes_mellitus__Modification_with_biofeedback_therapy_ L2 - https://www.nejm.org/doi/10.1056/NEJM198405173102003?url_ver=Z39.88-2003&rfr_id=ori:rid:crossref.org&rfr_dat=cr_pub=pubmed DB - PRIME DP - Unbound Medicine ER -