Diagnosis of anemia and iron deficiency: analytic and biological variations of laboratory tests.Am J Clin Nutr. 1984 Jun; 39(6):937-41.AJ
Abstract
We describe the magnitude of analytic errors and the within-subject biological variations for laboratory tests that are used in the diagnosis of anemia and iron deficiency. For Hb, hematocrit, and red cell indices, coefficients of variation for analytic and biological variations are less than 4%. In general, higher coefficients of variation are characteristic of serum iron, iron-binding capacity, serum ferritin, and erythrocyte protoporphyrin. Particularly high analytic variations between different laboratories have been described for iron-binding capacity and the greatest biological variations have been noted for serum iron. An awareness of these sources of error is helpful in designing studies and in interpreting laboratory results.
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MeSH
Pub Type(s)
Journal Article
Research Support, U.S. Gov't, P.H.S.
Language
eng
PubMed ID
6720622
Citation
Dallman, P R.. "Diagnosis of Anemia and Iron Deficiency: Analytic and Biological Variations of Laboratory Tests." The American Journal of Clinical Nutrition, vol. 39, no. 6, 1984, pp. 937-41.
Dallman PR. Diagnosis of anemia and iron deficiency: analytic and biological variations of laboratory tests. Am J Clin Nutr. 1984;39(6):937-41.
Dallman, P. R. (1984). Diagnosis of anemia and iron deficiency: analytic and biological variations of laboratory tests. The American Journal of Clinical Nutrition, 39(6), 937-41.
Dallman PR. Diagnosis of Anemia and Iron Deficiency: Analytic and Biological Variations of Laboratory Tests. Am J Clin Nutr. 1984;39(6):937-41. PubMed PMID: 6720622.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR
T1 - Diagnosis of anemia and iron deficiency: analytic and biological variations of laboratory tests.
A1 - Dallman,P R,
PY - 1984/6/1/pubmed
PY - 1984/6/1/medline
PY - 1984/6/1/entrez
SP - 937
EP - 41
JF - The American journal of clinical nutrition
JO - Am J Clin Nutr
VL - 39
IS - 6
N2 - We describe the magnitude of analytic errors and the within-subject biological variations for laboratory tests that are used in the diagnosis of anemia and iron deficiency. For Hb, hematocrit, and red cell indices, coefficients of variation for analytic and biological variations are less than 4%. In general, higher coefficients of variation are characteristic of serum iron, iron-binding capacity, serum ferritin, and erythrocyte protoporphyrin. Particularly high analytic variations between different laboratories have been described for iron-binding capacity and the greatest biological variations have been noted for serum iron. An awareness of these sources of error is helpful in designing studies and in interpreting laboratory results.
SN - 0002-9165
UR - https://www.unboundmedicine.com/medline/citation/6720622/Diagnosis_of_anemia_and_iron_deficiency:_analytic_and_biological_variations_of_laboratory_tests_
L2 - https://academic.oup.com/ajcn/article-lookup/doi/10.1093/ajcn/39.6.937
DB - PRIME
DP - Unbound Medicine
ER -