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Problems in the diagnosis and investigation of megaloblastic anemia.
Can Med Assoc J. 1980 May 10; 122(9):999-1004.CM

Abstract

The diagnosis of megaloblastic anemia and the differentiation of folate and vitamin B12 deficiency require, in addition to careful attention to the history and physical findings, the use of laboratory tests. In this paper the commonly ordered tests for such a diagnosis are discussed, with emphasis on the conditions that may cause false-positive or false-negative results in the complete blood count, examination of a peripheral blood smear and a bone marrow specimen, serum and erythrocyte folate assays, serum vitamin B12 assays, tests of vitamin B12 absorption and gastric analysis.

Authors

No affiliation info available

Pub Type(s)

Journal Article
Review

Language

eng

PubMed ID

6768440

Citation

Shojania, A M.. "Problems in the Diagnosis and Investigation of Megaloblastic Anemia." Canadian Medical Association Journal, vol. 122, no. 9, 1980, pp. 999-1004.
Shojania AM. Problems in the diagnosis and investigation of megaloblastic anemia. Can Med Assoc J. 1980;122(9):999-1004.
Shojania, A. M. (1980). Problems in the diagnosis and investigation of megaloblastic anemia. Canadian Medical Association Journal, 122(9), 999-1004.
Shojania AM. Problems in the Diagnosis and Investigation of Megaloblastic Anemia. Can Med Assoc J. 1980 May 10;122(9):999-1004. PubMed PMID: 6768440.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Problems in the diagnosis and investigation of megaloblastic anemia. A1 - Shojania,A M, PY - 1980/5/10/pubmed PY - 1980/5/10/medline PY - 1980/5/10/entrez SP - 999 EP - 1004 JF - Canadian Medical Association journal JO - Can Med Assoc J VL - 122 IS - 9 N2 - The diagnosis of megaloblastic anemia and the differentiation of folate and vitamin B12 deficiency require, in addition to careful attention to the history and physical findings, the use of laboratory tests. In this paper the commonly ordered tests for such a diagnosis are discussed, with emphasis on the conditions that may cause false-positive or false-negative results in the complete blood count, examination of a peripheral blood smear and a bone marrow specimen, serum and erythrocyte folate assays, serum vitamin B12 assays, tests of vitamin B12 absorption and gastric analysis. SN - 0008-4409 UR - https://www.unboundmedicine.com/medline/citation/6768440/Problems_in_the_diagnosis_and_investigation_of_megaloblastic_anemia_ L2 - https://www.ncbi.nlm.nih.gov/pmc/articles/pmid/6768440/ DB - PRIME DP - Unbound Medicine ER -