Tags

Type your tag names separated by a space and hit enter

The effect of a high cholesterol and saturated fat diet on serum high-density lipoprotein-cholesterol, apoprotein A-I, and apoprotein E levels in normolipidemic humans.
Am J Clin Nutr. 1980 Dec; 33(12):2559-65.AJ

Abstract

The effects of a high cholesterol, high saturated fat diet on serum high density lipoprotein cholesterol, apo A-I, and apo E levels were studied in six normolipidemic subjects. The study was done on an outpatient basis and mixed natural foods normally consumed by humans were used. When compared with a low cholesterol (98 mg/day) high polyunsaturated fat (P/S ratio 1.6) diet, the high cholesterol (1021 mg/day), high saturated fat (P/S ratio 0.4) diet increased serum cholesterol (23%) by raising the cholesterol concentration in very low-density lipoproteins (59%), low-density lipoproteins (15%), and high-density lipoproteins (30%). The low-density lipoprotein-cholesterol/high-density lipoprotein-cholesterol ratio fell significantly from 1.78 to 1.58. The increased high-density lipoprotein-cholesterol was associated with an elevation of serum apo A-I but not apo E. Serum triglycerides did not change significantly.

Authors

No affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info available

Pub Type(s)

Journal Article
Research Support, Non-U.S. Gov't
Research Support, U.S. Gov't, P.H.S.

Language

eng

PubMed ID

6776798

Citation

Tan, M H., et al. "The Effect of a High Cholesterol and Saturated Fat Diet On Serum High-density Lipoprotein-cholesterol, Apoprotein A-I, and Apoprotein E Levels in Normolipidemic Humans." The American Journal of Clinical Nutrition, vol. 33, no. 12, 1980, pp. 2559-65.
Tan MH, Dickinson MA, Albers JJ, et al. The effect of a high cholesterol and saturated fat diet on serum high-density lipoprotein-cholesterol, apoprotein A-I, and apoprotein E levels in normolipidemic humans. Am J Clin Nutr. 1980;33(12):2559-65.
Tan, M. H., Dickinson, M. A., Albers, J. J., Havel, R. J., Cheung, M. C., & Vigne, J. L. (1980). The effect of a high cholesterol and saturated fat diet on serum high-density lipoprotein-cholesterol, apoprotein A-I, and apoprotein E levels in normolipidemic humans. The American Journal of Clinical Nutrition, 33(12), 2559-65.
Tan MH, et al. The Effect of a High Cholesterol and Saturated Fat Diet On Serum High-density Lipoprotein-cholesterol, Apoprotein A-I, and Apoprotein E Levels in Normolipidemic Humans. Am J Clin Nutr. 1980;33(12):2559-65. PubMed PMID: 6776798.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - The effect of a high cholesterol and saturated fat diet on serum high-density lipoprotein-cholesterol, apoprotein A-I, and apoprotein E levels in normolipidemic humans. AU - Tan,M H, AU - Dickinson,M A, AU - Albers,J J, AU - Havel,R J, AU - Cheung,M C, AU - Vigne,J L, PY - 1980/12/1/pubmed PY - 1980/12/1/medline PY - 1980/12/1/entrez SP - 2559 EP - 65 JF - The American journal of clinical nutrition JO - Am J Clin Nutr VL - 33 IS - 12 N2 - The effects of a high cholesterol, high saturated fat diet on serum high density lipoprotein cholesterol, apo A-I, and apo E levels were studied in six normolipidemic subjects. The study was done on an outpatient basis and mixed natural foods normally consumed by humans were used. When compared with a low cholesterol (98 mg/day) high polyunsaturated fat (P/S ratio 1.6) diet, the high cholesterol (1021 mg/day), high saturated fat (P/S ratio 0.4) diet increased serum cholesterol (23%) by raising the cholesterol concentration in very low-density lipoproteins (59%), low-density lipoproteins (15%), and high-density lipoproteins (30%). The low-density lipoprotein-cholesterol/high-density lipoprotein-cholesterol ratio fell significantly from 1.78 to 1.58. The increased high-density lipoprotein-cholesterol was associated with an elevation of serum apo A-I but not apo E. Serum triglycerides did not change significantly. SN - 0002-9165 UR - https://www.unboundmedicine.com/medline/citation/6776798/The_effect_of_a_high_cholesterol_and_saturated_fat_diet_on_serum_high_density_lipoprotein_cholesterol_apoprotein_A_I_and_apoprotein_E_levels_in_normolipidemic_humans_ DB - PRIME DP - Unbound Medicine ER -