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Pathophysiology of swine dysentery: colonic transport and permeability studies.
J Infect Dis. 1980 Nov; 142(5):676-84.JI

Abstract

Net transport of electrolytes and water, unidirectional Na+ and Cl- fluxes, and mucosal permeability were examined in isolated colonic loops of control pigs and pigs infected with Treponema hyodysenteriae. Results indicated that all net ion and water absorption from the colon was abolished in infected pigs. This abolition of net absorption was almost exclusively the result of a decrease in the lumen-to-blood fluxes of Na+ and Cl-; the blood to lumen fluxes and mucosal permeability were essentially unaffected. The results indicated that the diarrhea observed in these pigs was a consequence of colonic absorptive failure alone. Neither an active nor a passive secretory process could explain the fluid losses under the conditions of these experiments.

Authors

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Pub Type(s)

Journal Article

Language

eng

PubMed ID

6780628

Citation

Argenzio, R A., et al. "Pathophysiology of Swine Dysentery: Colonic Transport and Permeability Studies." The Journal of Infectious Diseases, vol. 142, no. 5, 1980, pp. 676-84.
Argenzio RA, Whipp SC, Glock RD. Pathophysiology of swine dysentery: colonic transport and permeability studies. J Infect Dis. 1980;142(5):676-84.
Argenzio, R. A., Whipp, S. C., & Glock, R. D. (1980). Pathophysiology of swine dysentery: colonic transport and permeability studies. The Journal of Infectious Diseases, 142(5), 676-84.
Argenzio RA, Whipp SC, Glock RD. Pathophysiology of Swine Dysentery: Colonic Transport and Permeability Studies. J Infect Dis. 1980;142(5):676-84. PubMed PMID: 6780628.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Pathophysiology of swine dysentery: colonic transport and permeability studies. AU - Argenzio,R A, AU - Whipp,S C, AU - Glock,R D, PY - 1980/11/1/pubmed PY - 1980/11/1/medline PY - 1980/11/1/entrez SP - 676 EP - 84 JF - The Journal of infectious diseases JO - J. Infect. Dis. VL - 142 IS - 5 N2 - Net transport of electrolytes and water, unidirectional Na+ and Cl- fluxes, and mucosal permeability were examined in isolated colonic loops of control pigs and pigs infected with Treponema hyodysenteriae. Results indicated that all net ion and water absorption from the colon was abolished in infected pigs. This abolition of net absorption was almost exclusively the result of a decrease in the lumen-to-blood fluxes of Na+ and Cl-; the blood to lumen fluxes and mucosal permeability were essentially unaffected. The results indicated that the diarrhea observed in these pigs was a consequence of colonic absorptive failure alone. Neither an active nor a passive secretory process could explain the fluid losses under the conditions of these experiments. SN - 0022-1899 UR - https://www.unboundmedicine.com/medline/citation/6780628/Pathophysiology_of_swine_dysentery:_colonic_transport_and_permeability_studies_ L2 - https://academic.oup.com/jid/article-lookup/doi/10.1093/infdis/142.5.676 DB - PRIME DP - Unbound Medicine ER -