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[Variations of the plasma levels of gonadotrophins (FSH and LH) and of its response to stimulation with gonadotrophin releasing hormone (GnRH) with different plasma levels of prolactin (PRL) in women with the syndrome of galactorrhea-amenorrhea (author's transl)].
Med Clin (Barc). 1981 Feb 25; 76(4):164-8.MC

Abstract

In 15 women with either isolated amenorrhea or amenorrhea associated to galactorrhea the basal levels of PRL allowed a clear differentiation into three groups. The first group (n = 3) had normal PRL levels (x +/- SD, 8.0 +/- 4.8 ng/ml), the second group (n = 4) had moderately elevated PRL (25.6 +/- 6.5 ng/ml), and the third group (n = 8) had very high PRL (176.0 +/- 76.1 ng/ml). All the patients in the third group had a pituitary adenoma. In the three groups the basal levels of FSH and LH and their response to GnRH were measured with the purpose of uncovering possible relationships between these results and the levels of PRL, and the tumoral or non-tumoral origin of the hyperprolactinemia when it was present. No statistically significant differences were found amongst the three groups. The results suggest that hyperprolactinemia has no influence upon gonadotrophin release or the endogenous release of GnRH. The measurement of plasma gonadotrophins and their response to GnRH appears to be of no clinical value for the differential diagnosis of the hyperprolactinemias.

Authors

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Pub Type(s)

English Abstract
Journal Article

Language

spa

PubMed ID

6782394

Citation

Salmerón de Diego, J, et al. "[Variations of the Plasma Levels of Gonadotrophins (FSH and LH) and of Its Response to Stimulation With Gonadotrophin Releasing Hormone (GnRH) With Different Plasma Levels of Prolactin (PRL) in Women With the Syndrome of Galactorrhea-amenorrhea (author's Transl)]." Medicina Clinica, vol. 76, no. 4, 1981, pp. 164-8.
Salmerón de Diego J, Alonso Rodríguez C, Santos Reyero M, et al. [Variations of the plasma levels of gonadotrophins (FSH and LH) and of its response to stimulation with gonadotrophin releasing hormone (GnRH) with different plasma levels of prolactin (PRL) in women with the syndrome of galactorrhea-amenorrhea (author's transl)]. Med Clin (Barc). 1981;76(4):164-8.
Salmerón de Diego, J., Alonso Rodríguez, C., Santos Reyero, M., Salazar Orlando, A., & Palacios Mateos, J. M. (1981). [Variations of the plasma levels of gonadotrophins (FSH and LH) and of its response to stimulation with gonadotrophin releasing hormone (GnRH) with different plasma levels of prolactin (PRL) in women with the syndrome of galactorrhea-amenorrhea (author's transl)]. Medicina Clinica, 76(4), 164-8.
Salmerón de Diego J, et al. [Variations of the Plasma Levels of Gonadotrophins (FSH and LH) and of Its Response to Stimulation With Gonadotrophin Releasing Hormone (GnRH) With Different Plasma Levels of Prolactin (PRL) in Women With the Syndrome of Galactorrhea-amenorrhea (author's Transl)]. Med Clin (Barc). 1981 Feb 25;76(4):164-8. PubMed PMID: 6782394.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - [Variations of the plasma levels of gonadotrophins (FSH and LH) and of its response to stimulation with gonadotrophin releasing hormone (GnRH) with different plasma levels of prolactin (PRL) in women with the syndrome of galactorrhea-amenorrhea (author's transl)]. AU - Salmerón de Diego,J, AU - Alonso Rodríguez,C, AU - Santos Reyero,M, AU - Salazar Orlando,A, AU - Palacios Mateos,J M, PY - 1981/2/25/pubmed PY - 1981/2/25/medline PY - 1981/2/25/entrez SP - 164 EP - 8 JF - Medicina clinica JO - Med Clin (Barc) VL - 76 IS - 4 N2 - In 15 women with either isolated amenorrhea or amenorrhea associated to galactorrhea the basal levels of PRL allowed a clear differentiation into three groups. The first group (n = 3) had normal PRL levels (x +/- SD, 8.0 +/- 4.8 ng/ml), the second group (n = 4) had moderately elevated PRL (25.6 +/- 6.5 ng/ml), and the third group (n = 8) had very high PRL (176.0 +/- 76.1 ng/ml). All the patients in the third group had a pituitary adenoma. In the three groups the basal levels of FSH and LH and their response to GnRH were measured with the purpose of uncovering possible relationships between these results and the levels of PRL, and the tumoral or non-tumoral origin of the hyperprolactinemia when it was present. No statistically significant differences were found amongst the three groups. The results suggest that hyperprolactinemia has no influence upon gonadotrophin release or the endogenous release of GnRH. The measurement of plasma gonadotrophins and their response to GnRH appears to be of no clinical value for the differential diagnosis of the hyperprolactinemias. SN - 0025-7753 UR - https://www.unboundmedicine.com/medline/citation/6782394/[Variations_of_the_plasma_levels_of_gonadotrophins__FSH_and_LH__and_of_its_response_to_stimulation_with_gonadotrophin_releasing_hormone__GnRH__with_different_plasma_levels_of_prolactin__PRL__in_women_with_the_syndrome_of_galactorrhea_amenorrhea__author's_transl_]_ DB - PRIME DP - Unbound Medicine ER -