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[Treatment of Paget's disease of bone: diphosphonates or calcitonin?].
Schweiz Med Wochenschr. 1981 Apr 11; 111(15):518-24.SM

Abstract

During the past 6 years 16 patients suffering from Paget's disease of bone have been treated and regularly followed up in our department. 10 of these patients have received etidronate (ethane-hydroxy-diphosphonate), 4 others have received synthetic human calcitonin and the last 2 have received both treatments, first successively then simultaneously. Under either therapy satisfactory clinical and biological results have been observed (diminution of pain and decreased levels of serum alkaline phosphatase and hydroxyprolinuria). Etidronate has been more efficient in reducing biological parameters, whereas calcitonin has produced a faster symptomatic response. On the basis of these observations the present principles for treatment of Paget's disease are discussed.

Authors

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Pub Type(s)

Comparative Study
English Abstract
Journal Article

Language

fre

PubMed ID

6785879

Citation

Davoine, G A., et al. "[Treatment of Paget's Disease of Bone: Diphosphonates or Calcitonin?]." Schweizerische Medizinische Wochenschrift, vol. 111, no. 15, 1981, pp. 518-24.
Davoine GA, Jung A, Courvoisier B. [Treatment of Paget's disease of bone: diphosphonates or calcitonin?]. Schweiz Med Wochenschr. 1981;111(15):518-24.
Davoine, G. A., Jung, A., & Courvoisier, B. (1981). [Treatment of Paget's disease of bone: diphosphonates or calcitonin?]. Schweizerische Medizinische Wochenschrift, 111(15), 518-24.
Davoine GA, Jung A, Courvoisier B. [Treatment of Paget's Disease of Bone: Diphosphonates or Calcitonin?]. Schweiz Med Wochenschr. 1981 Apr 11;111(15):518-24. PubMed PMID: 6785879.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - [Treatment of Paget's disease of bone: diphosphonates or calcitonin?]. AU - Davoine,G A, AU - Jung,A, AU - Courvoisier,B, PY - 1981/4/11/pubmed PY - 1981/4/11/medline PY - 1981/4/11/entrez SP - 518 EP - 24 JF - Schweizerische medizinische Wochenschrift JO - Schweiz Med Wochenschr VL - 111 IS - 15 N2 - During the past 6 years 16 patients suffering from Paget's disease of bone have been treated and regularly followed up in our department. 10 of these patients have received etidronate (ethane-hydroxy-diphosphonate), 4 others have received synthetic human calcitonin and the last 2 have received both treatments, first successively then simultaneously. Under either therapy satisfactory clinical and biological results have been observed (diminution of pain and decreased levels of serum alkaline phosphatase and hydroxyprolinuria). Etidronate has been more efficient in reducing biological parameters, whereas calcitonin has produced a faster symptomatic response. On the basis of these observations the present principles for treatment of Paget's disease are discussed. SN - 0036-7672 UR - https://www.unboundmedicine.com/medline/citation/6785879/[Treatment_of_Paget's_disease_of_bone:_diphosphonates_or_calcitonin]_ L2 - https://medlineplus.gov/pagetsdiseaseofbone.html DB - PRIME DP - Unbound Medicine ER -