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[Effect of certain GABA-ergic substances on dopamine metabolism in the rat brain].
Farmakol Toksikol. 1981 Jan-Feb; 44(1):37-40.FT

Abstract

Effect of the GABA-ergic drugs, sodium hydroxybutyrate, n-dipropylacetate (n-DPA) and piracetam, has been studied on the level of homovanillic acid (HVA) and activity of GABA-transaminase in the striate body of the rat brain. It has been established that piracetam in doses of 500 and 400 mg/kg, n-DPA in a dose of 200 mg/kg and sodium hydroxybutyrate in a dose of 500 mg/kg do not affect the HVA level or activity of GABA-transaminase. The data obtained are likely to support a suggestion about a possible relationship between the GABA-ergic and dopaminergic mediator system.

Authors

No affiliation info availableNo affiliation info available

Pub Type(s)

Comparative Study
English Abstract
Journal Article

Language

rus

PubMed ID

6790298

Citation

Malikova, L A., and V A. Arefolov. "[Effect of Certain GABA-ergic Substances On Dopamine Metabolism in the Rat Brain]." Farmakologiia I Toksikologiia, vol. 44, no. 1, 1981, pp. 37-40.
Malikova LA, Arefolov VA. [Effect of certain GABA-ergic substances on dopamine metabolism in the rat brain]. Farmakol Toksikol. 1981;44(1):37-40.
Malikova, L. A., & Arefolov, V. A. (1981). [Effect of certain GABA-ergic substances on dopamine metabolism in the rat brain]. Farmakologiia I Toksikologiia, 44(1), 37-40.
Malikova LA, Arefolov VA. [Effect of Certain GABA-ergic Substances On Dopamine Metabolism in the Rat Brain]. Farmakol Toksikol. 1981 Jan-Feb;44(1):37-40. PubMed PMID: 6790298.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - [Effect of certain GABA-ergic substances on dopamine metabolism in the rat brain]. AU - Malikova,L A, AU - Arefolov,V A, PY - 1981/1/1/pubmed PY - 1981/1/1/medline PY - 1981/1/1/entrez SP - 37 EP - 40 JF - Farmakologiia i toksikologiia JO - Farmakol Toksikol VL - 44 IS - 1 N2 - Effect of the GABA-ergic drugs, sodium hydroxybutyrate, n-dipropylacetate (n-DPA) and piracetam, has been studied on the level of homovanillic acid (HVA) and activity of GABA-transaminase in the striate body of the rat brain. It has been established that piracetam in doses of 500 and 400 mg/kg, n-DPA in a dose of 200 mg/kg and sodium hydroxybutyrate in a dose of 500 mg/kg do not affect the HVA level or activity of GABA-transaminase. The data obtained are likely to support a suggestion about a possible relationship between the GABA-ergic and dopaminergic mediator system. SN - 0014-8318 UR - https://www.unboundmedicine.com/medline/citation/6790298/[Effect_of_certain_GABA_ergic_substances_on_dopamine_metabolism_in_the_rat_brain]_ L2 - https://medlineplus.gov/clubdrugs.html DB - PRIME DP - Unbound Medicine ER -