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Neonatal effects of maternal administration of acebutolol.
Br Med J (Clin Res Ed). 1981 Oct 24; 283(6299):1077-9.BM

Abstract

Systolic blood pressure, heart rate, and blood glucose concentration were measured in the first three days of life in 10 infants born to mothers who had received acebutolol, a cardioselective beta-adrenergic-blocking agent, for hypertension in pregnancy and compared with values in 10 infants whose mothers had received methyldopa. The blood pressure was expressed as a percentage of the expected value. Blood pressure was significantly lower in the infants of the mothers given acebutolol (p less than 0.02, less than 0.01, and less than 0.01 respectively during the three days of observation). Heart rate was also lower, but the significance was only at the 0.05 level. Blood glucose was not significantly different between the two groups. These results suggest that care should be taken in prescribing beta-adrenergic-blocking drugs during pregnancy.

Authors

No affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info available

Pub Type(s)

Journal Article

Language

eng

PubMed ID

6794766

Citation

Dumez, Y, et al. "Neonatal Effects of Maternal Administration of Acebutolol." British Medical Journal (Clinical Research Ed.), vol. 283, no. 6299, 1981, pp. 1077-9.
Dumez Y, Tchobroutsky C, Hornych H, et al. Neonatal effects of maternal administration of acebutolol. Br Med J (Clin Res Ed). 1981;283(6299):1077-9.
Dumez, Y., Tchobroutsky, C., Hornych, H., & Amiel-Tison, C. (1981). Neonatal effects of maternal administration of acebutolol. British Medical Journal (Clinical Research Ed.), 283(6299), 1077-9.
Dumez Y, et al. Neonatal Effects of Maternal Administration of Acebutolol. Br Med J (Clin Res Ed). 1981 Oct 24;283(6299):1077-9. PubMed PMID: 6794766.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Neonatal effects of maternal administration of acebutolol. AU - Dumez,Y, AU - Tchobroutsky,C, AU - Hornych,H, AU - Amiel-Tison,C, PY - 1981/10/24/pubmed PY - 1981/10/24/medline PY - 1981/10/24/entrez SP - 1077 EP - 9 JF - British medical journal (Clinical research ed.) JO - Br Med J (Clin Res Ed) VL - 283 IS - 6299 N2 - Systolic blood pressure, heart rate, and blood glucose concentration were measured in the first three days of life in 10 infants born to mothers who had received acebutolol, a cardioselective beta-adrenergic-blocking agent, for hypertension in pregnancy and compared with values in 10 infants whose mothers had received methyldopa. The blood pressure was expressed as a percentage of the expected value. Blood pressure was significantly lower in the infants of the mothers given acebutolol (p less than 0.02, less than 0.01, and less than 0.01 respectively during the three days of observation). Heart rate was also lower, but the significance was only at the 0.05 level. Blood glucose was not significantly different between the two groups. These results suggest that care should be taken in prescribing beta-adrenergic-blocking drugs during pregnancy. SN - 0267-0623 UR - https://www.unboundmedicine.com/medline/citation/6794766/Neonatal_effects_of_maternal_administration_of_acebutolol_ L2 - https://www.ncbi.nlm.nih.gov/pmc/articles/pmid/6794766/ DB - PRIME DP - Unbound Medicine ER -