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Restoration of ovarian function by low nocturnal single daily doses of bromocriptine in patients with the galactorrhea-amenorrhea syndrome.
Fertil Steril. 1982 Mar; 37(3):392-6.FS

Abstract

Eighteen hyperprolactinemic patients with either amenorrhea or both galactorrhea and amenorrhea were treated with 2.5 mg of bromocriptine per day supplied at night. Ovulation occurred in 16 patients, and 8 wishing to conceive became pregnant. One of these patients became pregnant for a second time at a bromocriptine dose as low as 1.25 mg/day. Normal ovulatory cycles in four women receiving 2.5 mg of bromocriptine per day could also be maintained at 1.25 mg, despite the differences in the degree of prolactin (PRL) inhibition. Progesterone and luteinizing hormone levels measured for both bromocriptine levels were consistent with ovulatory cycles. The low, single dose of bromocriptine per day supplied at night decreased PRL levels, but normalization of blood levels did not always occur. Eighty percent of the patients ovulated with prolactin values over 25 ng/ml (normal value = less than 20 ng/ml).

Authors

No affiliation info availableNo affiliation info available

Pub Type(s)

Journal Article

Language

eng

PubMed ID

6800849

Citation

de Bernal, M, and M de Villamizar. "Restoration of Ovarian Function By Low Nocturnal Single Daily Doses of Bromocriptine in Patients With the Galactorrhea-amenorrhea Syndrome." Fertility and Sterility, vol. 37, no. 3, 1982, pp. 392-6.
de Bernal M, de Villamizar M. Restoration of ovarian function by low nocturnal single daily doses of bromocriptine in patients with the galactorrhea-amenorrhea syndrome. Fertil Steril. 1982;37(3):392-6.
de Bernal, M., & de Villamizar, M. (1982). Restoration of ovarian function by low nocturnal single daily doses of bromocriptine in patients with the galactorrhea-amenorrhea syndrome. Fertility and Sterility, 37(3), 392-6.
de Bernal M, de Villamizar M. Restoration of Ovarian Function By Low Nocturnal Single Daily Doses of Bromocriptine in Patients With the Galactorrhea-amenorrhea Syndrome. Fertil Steril. 1982;37(3):392-6. PubMed PMID: 6800849.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Restoration of ovarian function by low nocturnal single daily doses of bromocriptine in patients with the galactorrhea-amenorrhea syndrome. AU - de Bernal,M, AU - de Villamizar,M, PY - 1982/3/1/pubmed PY - 1982/3/1/medline PY - 1982/3/1/entrez SP - 392 EP - 6 JF - Fertility and sterility JO - Fertil Steril VL - 37 IS - 3 N2 - Eighteen hyperprolactinemic patients with either amenorrhea or both galactorrhea and amenorrhea were treated with 2.5 mg of bromocriptine per day supplied at night. Ovulation occurred in 16 patients, and 8 wishing to conceive became pregnant. One of these patients became pregnant for a second time at a bromocriptine dose as low as 1.25 mg/day. Normal ovulatory cycles in four women receiving 2.5 mg of bromocriptine per day could also be maintained at 1.25 mg, despite the differences in the degree of prolactin (PRL) inhibition. Progesterone and luteinizing hormone levels measured for both bromocriptine levels were consistent with ovulatory cycles. The low, single dose of bromocriptine per day supplied at night decreased PRL levels, but normalization of blood levels did not always occur. Eighty percent of the patients ovulated with prolactin values over 25 ng/ml (normal value = less than 20 ng/ml). SN - 0015-0282 UR - https://www.unboundmedicine.com/medline/citation/6800849/Restoration_of_ovarian_function_by_low_nocturnal_single_daily_doses_of_bromocriptine_in_patients_with_the_galactorrhea_amenorrhea_syndrome_ L2 - https://linkinghub.elsevier.com/retrieve/pii/S0015-0282(16)46102-9 DB - PRIME DP - Unbound Medicine ER -