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Significance of hyperprolactinemia in 70 women with amenorrhea.
Isr J Med Sci. 1978 Jul; 14(7):753-61.IJ

Abstract

The clinical, radiological and hormonal findings in 70 amenorrheic patients are described. Hyperprolactinemia was found in 18 patients (25.7%) who were divided into three groups: nine patients with functional secondary amenorrhea, six patients with radiological evidence of pituitary tumor, and three patients with primary amenorrhea. One of the latter group had primary hypothyroidism. Plasma gonadotropin concentrations were normal or low in most patients, with the exception of five women with ovarian failure in whom the levels were significantly raised. Galactorrhea was diagnosed in 23 patients (32.8%), and in 16 of them plasma prolactin levels were elevated. Recent experience has shown that reduction of prolactin levels to normal by removal of prolactin-secreting tumors or by treatment with bromocriptine results in the restoration of normal menstrual cycles and fertility. The hormonal and radiological identification and characterization of hyperprolactinemic amenorrhea are therefore of prime importance.

Authors

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Pub Type(s)

Journal Article

Language

eng

PubMed ID

681167

Citation

Potashnik, G, et al. "Significance of Hyperprolactinemia in 70 Women With Amenorrhea." Israel Journal of Medical Sciences, vol. 14, no. 7, 1978, pp. 753-61.
Potashnik G, Bar-Ziv J, Glick S, et al. Significance of hyperprolactinemia in 70 women with amenorrhea. Isr J Med Sci. 1978;14(7):753-61.
Potashnik, G., Bar-Ziv, J., Glick, S., Shoham, A., & Ben-Aderet, N. (1978). Significance of hyperprolactinemia in 70 women with amenorrhea. Israel Journal of Medical Sciences, 14(7), 753-61.
Potashnik G, et al. Significance of Hyperprolactinemia in 70 Women With Amenorrhea. Isr J Med Sci. 1978;14(7):753-61. PubMed PMID: 681167.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Significance of hyperprolactinemia in 70 women with amenorrhea. AU - Potashnik,G, AU - Bar-Ziv,J, AU - Glick,S, AU - Shoham,A, AU - Ben-Aderet,N, PY - 1978/7/1/pubmed PY - 1978/7/1/medline PY - 1978/7/1/entrez SP - 753 EP - 61 JF - Israel journal of medical sciences JO - Isr J Med Sci VL - 14 IS - 7 N2 - The clinical, radiological and hormonal findings in 70 amenorrheic patients are described. Hyperprolactinemia was found in 18 patients (25.7%) who were divided into three groups: nine patients with functional secondary amenorrhea, six patients with radiological evidence of pituitary tumor, and three patients with primary amenorrhea. One of the latter group had primary hypothyroidism. Plasma gonadotropin concentrations were normal or low in most patients, with the exception of five women with ovarian failure in whom the levels were significantly raised. Galactorrhea was diagnosed in 23 patients (32.8%), and in 16 of them plasma prolactin levels were elevated. Recent experience has shown that reduction of prolactin levels to normal by removal of prolactin-secreting tumors or by treatment with bromocriptine results in the restoration of normal menstrual cycles and fertility. The hormonal and radiological identification and characterization of hyperprolactinemic amenorrhea are therefore of prime importance. SN - 0021-2180 UR - https://www.unboundmedicine.com/medline/citation/681167/Significance_of_hyperprolactinemia_in_70_women_with_amenorrhea_ L2 - http://www.diseaseinfosearch.org/result/2971 DB - PRIME DP - Unbound Medicine ER -