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Body shape in young children with homozygous sickle cell disease.

Abstract

Body shape, defined by detailed anthropometric measurement, was compared in 64 children with homozygous sickle cell (SS) disease, and in 123 children with a normal hemoglobin (AA) genotype, aged 4 to 6 years. Children with homozygous sickle cell disease showed an average reduction in weight, height, sitting height, limb length, interacromial and intercristal diameters, and skinfold thickness. They showed increased anteroposterior chest diameters with an increased anteroposterior-lateral chest diameter ratio. This report establishes that the effect of homozygous sickle cell disease on growth patterns in childhood is apparent before the age of 6 years. The relationship to changes in body shape, seen during adolescence and in affected adults, and their possible determinants, are discussed.

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  • Publisher Full Text
  • Authors

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    Source

    Pediatrics 71:4 1983 Apr pg 610-4

    MeSH

    Anemia, Sickle Cell
    Anthropometry
    Body Height
    Body Weight
    Cephalometry
    Child
    Child, Preschool
    Female
    Humans
    Male
    Skinfold Thickness

    Pub Type(s)

    Journal Article

    Language

    eng

    PubMed ID

    6835741

    Citation

    Stevens, M C., et al. "Body Shape in Young Children With Homozygous Sickle Cell Disease." Pediatrics, vol. 71, no. 4, 1983, pp. 610-4.
    Stevens MC, Hayes RJ, Serjeant GR. Body shape in young children with homozygous sickle cell disease. Pediatrics. 1983;71(4):610-4.
    Stevens, M. C., Hayes, R. J., & Serjeant, G. R. (1983). Body shape in young children with homozygous sickle cell disease. Pediatrics, 71(4), pp. 610-4.
    Stevens MC, Hayes RJ, Serjeant GR. Body Shape in Young Children With Homozygous Sickle Cell Disease. Pediatrics. 1983;71(4):610-4. PubMed PMID: 6835741.
    * Article titles in AMA citation format should be in sentence-case
    TY - JOUR T1 - Body shape in young children with homozygous sickle cell disease. AU - Stevens,M C, AU - Hayes,R J, AU - Serjeant,G R, PY - 1983/4/1/pubmed PY - 1983/4/1/medline PY - 1983/4/1/entrez SP - 610 EP - 4 JF - Pediatrics JO - Pediatrics VL - 71 IS - 4 N2 - Body shape, defined by detailed anthropometric measurement, was compared in 64 children with homozygous sickle cell (SS) disease, and in 123 children with a normal hemoglobin (AA) genotype, aged 4 to 6 years. Children with homozygous sickle cell disease showed an average reduction in weight, height, sitting height, limb length, interacromial and intercristal diameters, and skinfold thickness. They showed increased anteroposterior chest diameters with an increased anteroposterior-lateral chest diameter ratio. This report establishes that the effect of homozygous sickle cell disease on growth patterns in childhood is apparent before the age of 6 years. The relationship to changes in body shape, seen during adolescence and in affected adults, and their possible determinants, are discussed. SN - 0031-4005 UR - https://www.unboundmedicine.com/medline/citation/6835741/Body_shape_in_young_children_with_homozygous_sickle_cell_disease_ L2 - http://pediatrics.aappublications.org/cgi/pmidlookup?view=long&pmid=6835741 DB - PRIME DP - Unbound Medicine ER -