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Acceleration of wound healing by topical application of honey. An animal model.
Am J Surg 1983; 145(3):374-6AJ

Abstract

Commercial unboiled honey was applied topically to open wounds of 12 mice. Twelve other mice served as a control group and their wounds were dressed with saline solution only. Wound healing was judged histopathologically by measuring the thickness of granulation tissue, epithelization from the periphery of the wound, and the size of the open wounds. The animals were killed 3, 6, and 9 days from the day they were wounded and treated, and their wounds were examined histopathologically. According to the three mentioned criteria, wounds of the honey-treated animals healed much faster than the wounds of the control animals (p less than 0.001). Unboiled commercial honey seems to accelerate wound healing when applied topically due to its energy-producing properties, its hygroscopic effect on the wound, and its bacteriocidic properties. Our results suggest that honey applied topically on open wounds accelerates the healing process.

Authors

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Pub Type(s)

Journal Article

Language

eng

PubMed ID

6837863

Citation

Bergman, A, et al. "Acceleration of Wound Healing By Topical Application of Honey. an Animal Model." American Journal of Surgery, vol. 145, no. 3, 1983, pp. 374-6.
Bergman A, Yanai J, Weiss J, et al. Acceleration of wound healing by topical application of honey. An animal model. Am J Surg. 1983;145(3):374-6.
Bergman, A., Yanai, J., Weiss, J., Bell, D., & David, M. P. (1983). Acceleration of wound healing by topical application of honey. An animal model. American Journal of Surgery, 145(3), pp. 374-6.
Bergman A, et al. Acceleration of Wound Healing By Topical Application of Honey. an Animal Model. Am J Surg. 1983;145(3):374-6. PubMed PMID: 6837863.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Acceleration of wound healing by topical application of honey. An animal model. AU - Bergman,A, AU - Yanai,J, AU - Weiss,J, AU - Bell,D, AU - David,M P, PY - 1983/3/1/pubmed PY - 1983/3/1/medline PY - 1983/3/1/entrez SP - 374 EP - 6 JF - American journal of surgery JO - Am. J. Surg. VL - 145 IS - 3 N2 - Commercial unboiled honey was applied topically to open wounds of 12 mice. Twelve other mice served as a control group and their wounds were dressed with saline solution only. Wound healing was judged histopathologically by measuring the thickness of granulation tissue, epithelization from the periphery of the wound, and the size of the open wounds. The animals were killed 3, 6, and 9 days from the day they were wounded and treated, and their wounds were examined histopathologically. According to the three mentioned criteria, wounds of the honey-treated animals healed much faster than the wounds of the control animals (p less than 0.001). Unboiled commercial honey seems to accelerate wound healing when applied topically due to its energy-producing properties, its hygroscopic effect on the wound, and its bacteriocidic properties. Our results suggest that honey applied topically on open wounds accelerates the healing process. SN - 0002-9610 UR - https://www.unboundmedicine.com/medline/citation/6837863/Acceleration_of_wound_healing_by_topical_application_of_honey__An_animal_model_ L2 - https://linkinghub.elsevier.com/retrieve/pii/0002-9610(83)90204-0 DB - PRIME DP - Unbound Medicine ER -