Tags

Type your tag names separated by a space and hit enter

Experimental allergic orchitis induced by unilateral intratesticular bacterial infection in guinea-pigs.
Immunology. 1983 May; 49(1):45-51.I

Abstract

Inoculation of 1 X 10(3) viable Listeria monocytogenes into unilateral testis induced pathological changes in the contralateral testis and epididymis in guinea-pigs. Because L. Monocytogenes was not detected in the contralateral testis, liver or spleen during the period of the experiment, that is, bacterial growth was limited to the inoculated site, the pathological changes in the contralateral testis may be due to autoimmune mechanisms, but not due to bacterial inflammation. The pathological changes in our system were similar to those observed after the injection of testicular antigen in Freund's complete adjuvant. Delayed-in-onset erythematous skin reaction against testicular antigen and antisperm antibody in sera were detected in the guinea-pigs. The animal model in our system is a new one in which experimental autoimmune orchitis is induced by bacterial infection.

Authors

No affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info available

Pub Type(s)

Journal Article
Research Support, Non-U.S. Gov't

Language

eng

PubMed ID

6840807

Citation

Sanui, H, et al. "Experimental Allergic Orchitis Induced By Unilateral Intratesticular Bacterial Infection in Guinea-pigs." Immunology, vol. 49, no. 1, 1983, pp. 45-51.
Sanui H, Yoshida S, Himeno K, et al. Experimental allergic orchitis induced by unilateral intratesticular bacterial infection in guinea-pigs. Immunology. 1983;49(1):45-51.
Sanui, H., Yoshida, S., Himeno, K., & Nomoto, K. (1983). Experimental allergic orchitis induced by unilateral intratesticular bacterial infection in guinea-pigs. Immunology, 49(1), 45-51.
Sanui H, et al. Experimental Allergic Orchitis Induced By Unilateral Intratesticular Bacterial Infection in Guinea-pigs. Immunology. 1983;49(1):45-51. PubMed PMID: 6840807.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Experimental allergic orchitis induced by unilateral intratesticular bacterial infection in guinea-pigs. AU - Sanui,H, AU - Yoshida,S, AU - Himeno,K, AU - Nomoto,K, PY - 1983/5/1/pubmed PY - 1983/5/1/medline PY - 1983/5/1/entrez SP - 45 EP - 51 JF - Immunology JO - Immunology VL - 49 IS - 1 N2 - Inoculation of 1 X 10(3) viable Listeria monocytogenes into unilateral testis induced pathological changes in the contralateral testis and epididymis in guinea-pigs. Because L. Monocytogenes was not detected in the contralateral testis, liver or spleen during the period of the experiment, that is, bacterial growth was limited to the inoculated site, the pathological changes in the contralateral testis may be due to autoimmune mechanisms, but not due to bacterial inflammation. The pathological changes in our system were similar to those observed after the injection of testicular antigen in Freund's complete adjuvant. Delayed-in-onset erythematous skin reaction against testicular antigen and antisperm antibody in sera were detected in the guinea-pigs. The animal model in our system is a new one in which experimental autoimmune orchitis is induced by bacterial infection. SN - 0019-2805 UR - https://www.unboundmedicine.com/medline/citation/6840807/Experimental_allergic_orchitis_induced_by_unilateral_intratesticular_bacterial_infection_in_guinea_pigs_ L2 - https://www.ncbi.nlm.nih.gov/pmc/articles/pmid/6840807/ DB - PRIME DP - Unbound Medicine ER -